Results 21 to 30 of about 587 (136)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism [PDF]

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +2 more sources

THE EFFICACY OF MELDONIUM IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC ETIOLOGY WITH COMORBIDITIES [PDF]

Медицинский совет, 2017
Нeart failure is common both in cardiac and noncardiac disease. We conducted a study that showed high efficacy and safety of meldonium in patients with heart failure and comorbidity.
M. E. Statsenko, S. V. Turkina, S. V. Fabritskaya, I. A. Tyschenko, L. V. Poletayeva   +4 more
doaj   +2 more sources

Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19. [PDF]

Int J Mol Sci, 2021
Funding Information: Funding: This study was supported by the Latvian State Research Program project VPP‐COVID‐ 2020/1‐0014 ʺTowards new therapeutic and prophylactic treatments against Covid‐19 and corona‐ virusesʺ.
Vilskersts R, Kigitovica D, Korzh S, Videja M, Vilks K, Cirule H, Skride A, Makrecka-Kuka M, Liepinsh E, Dambrova M.   +9 more
europepmc   +2 more sources

The Effects of a Meldonium Pre-Treatment on the Course of the Faecal-Induced Sepsis in Rats. [PDF]

Int J Mol Sci, 2021
Sepsis is a life-threatening condition caused by the dysregulated and overwhelming response to infection, accompanied by an exaggerated pro-inflammatory state and lipid metabolism disturbance leading to sequential organ failure.
Đurašević S, Ružičić A, Lakić I, Tosti T, Đurović S, Glumac S, Pavlović S, Borković-Mitić S, Grigorov I, Stanković S, Jasnić N, Đorđević J, Todorović Z.   +12 more
europepmc   +3 more sources

Application of Meldonium for the Treatment of Patients with Diabetic Nephropathy

Львівський клінічний вісник, 2013
Introduction. Today, the life expectancy of people with diabetes mellitus (DM) has increased by several times. Mortality due to the acute complications of diabetes, such as diabetic coma, does not exceed 1.0%.
І. І. Топчій
doaj   +2 more sources

Meldonium and human sport performance: a narrative review evaluating the evidence for ergogenic potential [PDF]

Frontiers in Sports and Active Living
Meldonium has attracted considerable attention in sports due to its suggested effects on energy metabolism and high-profile doping cases. This narrative review evaluates Meldonium's biochemical mechanisms, pharmacokinetics, safety profile, and the ...
Christer Malm, Christer Malm, Michael Svensson, Michael Svensson   +3 more
doaj   +2 more sources

MELDONIUM EFFICACY IN CHRONIC CEREBROVASCULAR DISEASES [PDF]

Медицинский совет, 2016
The evidential base of meldonium in chronic cerebral ischemia is critically reviewed in the article.
M. A. DOMASHENKO, M. Yu. MAKSIMOVA
doaj   +2 more sources

EFFICACY OF MELDONIUM IN ACUTE PERIOD OF ISCHEMIC STROKE

Alʹmanah Kliničeskoj Mediciny, 2016
Background: As long as systemic thrombolysis is indicated to not more than 10% of patients with ischemic stroke, the search for medical agents for basic treatment of stroke is an important problem of today’s neurology.Aim: To evaluate efficacy of ...
S. V. Kotov, E. V. Isakova, T. V. Volchenkova, L. V. Smetana, S. N. Belkina   +4 more
doaj   +2 more sources

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025 [PDF]

Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +2 more sources

Meldonium, as a potential neuroprotective agent, promotes neuronal survival by protecting mitochondria in cerebral ischemia–reperfusion injury [PDF]

Journal of Translational Medicine
Background Stroke is a globally dangerous disease capable of causing irreversible neuronal damage with limited therapeutic options. Meldonium, an inhibitor of carnitine-dependent metabolism, is considered an anti-ischemic drug.
Weijie Yang, Xiuxing Lei, Fengying Liu, Xin Sui, Yi Yang, Zhenyu Xiao, Ziqi cui, Yangyang Sun, Jun Yang, Xinyi Yang, Xueyang Lin, Zhenghao Bao, Weidong Li, Yingkai Ma, Yongan Wang, Yuan Luo   +15 more
doaj   +2 more sources