Results 11 to 20 of about 364 (156)
CYTOPROTECTIVE EFFECT OF MELDONIUM ON CARDIOMYOCYTE
Arta Medica, 2023 Background. The use of myocardial cytoprotectors (meldonium) in patients with exertional angina is a scientific-practical dilemma. Material and methods. An open randomized clinical trial was conducted involving 160 patients with chronic heart failure (
Olga Chetruș
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Meldonium and neuroprotection. Theory, experiment and clinical practice.
Medičnì Perspektivi, 2018 In this review the possibilities of correction of brain metabolism in cases of acute cerebral ischemia (ACI) under using meldonium were considered. The biochemical specificity of this remedy in Krebs cycle, influence on cerebral glycolysis, by activating
V. P. Muslin, O. V. Pohorielov
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MELDONIUM EFFICACY IN CHRONIC CEREBROVASCULAR DISEASES
Медицинский совет, 2016 The evidential base of meldonium in chronic cerebral ischemia is critically reviewed in the article.
M. A. DOMASHENKO, M. Yu. MAKSIMOVA
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EFFICACY OF MELDONIUM IN ACUTE PERIOD OF ISCHEMIC STROKE
Alʹmanah Kliničeskoj Mediciny, 2016 Background: As long as systemic thrombolysis is indicated to not more than 10% of patients with ischemic stroke, the search for medical agents for basic treatment of stroke is an important problem of today’s neurology.Aim: To evaluate efficacy of ...
S. V. Kotov +4 more
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Application of Meldonium for the Treatment of Patients with Diabetic Nephropathy [PDF]
Львівський клінічний вісник, 2013 Introduction. Today, the life expectancy of people with diabetes mellitus (DM) has increased by several times. Mortality due to the acute complications of diabetes, such as diabetic coma, does not exceed 1.0%.
І. І. Топчій
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Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism. [PDF]
Adv Sci (Weinh)Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Edwards RS +8 more
europepmc +2 more sources
Annual Banned-Substance Review 18th Edition-Analytical Approaches in Human Sports Drug Testing 2024/2025. [PDF]
Drug Test AnalNew insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Thevis M, Kuuranne T, Geyer H.
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Hyperpolarized magnetic resonance shows that the anti‐ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post‐ischemic function in the diabetic heart [PDF]
NMR in Biomedicine, 2021 Kerstin Timm +2 more
exaly +2 more sources
Медицинский совет, 2022 Introduction. The number of patients with chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) is increasing every year. In both CHF and COPD, secondary mitochondrial dysfunction is observed.
M. E. Statsenko +3 more
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Angewandte Chemie, Volume 134, Issue 30, July 25, 2022., 2022 DfmD is a highly divergent member of the 2‐oxoglutarate‐dependent dioxygenase superfamily that catalyzes desaturation, rearrangement and demethylation of its substrate. In vitro biochemical studies and homology modeling suggest that these transformations occur via novel chemistry.
Elizabeth I. Parkinson +5 more
wiley +2 more sources