Results 1 to 10 of about 160 (142)
Proton nuclear magnetic resonance of some bis(organosilyl)methylhydrazines
Blake Bichlmeir, Robert West
exaly +2 more sources
The reaction of peptides and insulin with methylhydrazine [PDF]
BRADBURY JH.
openaire +3 more sources
Mutagenic potency of MMS-induced 1meA/3meC lesions in E. coli. [PDF]
The mutagenic activity of MMS in E. coli depends on the susceptibility of DNA bases to methylation and their repair by cellular defense systems. Among the lesions in methylated DNA is 1meA/3meC, which is recently recognized as being mutagenic.
Janion, Celina +15 more
core +1 more source
Lethal and mutagenic properties of MMS-generated DNA lesions in Escherichia coli cells deficient in BER and AlkB-directed DNA repair. [PDF]
Methylmethane sulphonate (MMS), an S(N)2-type alkylating agent, generates DNA methylated bases exhibiting cytotoxic and mutagenic properties. Such damaged bases can be removed by a system of base excision repair (BER) and by oxidative DNA demethylation ...
Sikora, Anna +11 more
core +1 more source
Experimental Studies with Methylhydrazine Derivatives [PDF]
SummaryNatulan (Procarbazine) is a methylhydrazine derivative which in animal experiments inhibits a series of transplantable tumours. The Walker carcinoma is markedly affected. Even well established Walker tumours disappear completely under Natulan treatment. Tumour tissue is replaced by fibrous tissue.
openaire +2 more sources
Herein we provide an overview of photochromic and photophysical properties of a broad variety of arylazo‐1,3,5‐trimethylpyrazole photoswitches, including the influence of 23 different para‐substituents. Measured half‐lives correlated in a Hammet plot are rationalized by density functional theory calculations, revealing the underlying thermal ...
Katharina Schlögl +6 more
wiley +2 more sources
The reaction of nitrilimines (2) with 1-substituted-1-methylhydrazines (3–6) led to the formation of the respective amidrazones (7) when R = CH3, Ph, and to the acyclic adducts (8,9) when R = CHO and COCH3. The acyclic adducts underwent thermal oxidative
El-Sawi, Emtithal A +3 more
core +1 more source
A Fluorogenic Hydrazino‐Pictet–Spengler Reaction in Live Cells
A fluorogenic hydrazino‐Pictet–Spengler (HIPS) ligation reaction is used to label lipid‐derived aldehydes under wash‐free conditions in live cells. This innovative technique enables wash‐free imaging within biological systems, offering invaluable insights into the extent and localization of oxidative stress.
Kaleena Basran, Nathan W. Luedtke
wiley +2 more sources

