Results 1 to 10 of about 160 (141)

Preparation of Some Acylated Methylhydrazines. [PDF]

open access: yesActa Chemica Scandinavica, 1964
Roger Stevens   +2 more
exaly   +2 more sources

Experimental Studies with Methylhydrazine Derivatives [PDF]

open access: yesActa geneticae medicae et gemellologiae, 1968
SummaryNatulan (Procarbazine) is a methylhydrazine derivative which in animal experiments inhibits a series of transplantable tumours. The Walker carcinoma is markedly affected. Even well established Walker tumours disappear completely under Natulan treatment. Tumour tissue is replaced by fibrous tissue.
openaire   +2 more sources

Mechanistic Insight into Para‐Substituent Control of Thermal Half‐Lives in Arylazopyrazole Photoswitches

open access: yesAngewandte Chemie, Volume 137, Issue 43, October 20, 2025.
Herein we provide an overview of photochromic and photophysical properties of a broad variety of arylazo‐1,3,5‐trimethylpyrazole photoswitches, including the influence of 23 different para‐substituents. Measured half‐lives correlated in a Hammet plot are rationalized by density functional theory calculations, revealing the underlying thermal ...
Katharina Schlögl   +6 more
wiley   +2 more sources

A Fluorogenic Hydrazino‐Pictet–Spengler Reaction in Live Cells

open access: yesAngewandte Chemie, Volume 137, Issue 40, September 26, 2025.
A fluorogenic hydrazino‐Pictet–Spengler (HIPS) ligation reaction is used to label lipid‐derived aldehydes under wash‐free conditions in live cells. This innovative technique enables wash‐free imaging within biological systems, offering invaluable insights into the extent and localization of oxidative stress.
Kaleena Basran, Nathan W. Luedtke
wiley   +2 more sources

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra   +11 more
wiley   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

open access: yesThe Chemical Record, Volume 26, Issue 6, June 2026.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Synthesis and Biological Profile of Substituted Pyrrolidinyl Carboxamides for Acyl‐ACP Thioesterase Inhibition

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 12, 23 March 2026.
The work outlined herein covers a series of novel herbicidal lead structures that possess a pyrrolidinyl pyrazole carboxamide scaffold as a key structural feature, carrying further substituted benzyl side chains. Based on scaffold hopping approaches from known fungicidal and herbicidal compounds and utilizing an optimized synthetic approach, a broader ...
Elisabeth Asmus   +24 more
wiley   +1 more source

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