Results 21 to 30 of about 160 (142)

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐Dioxide Derivatives

open access: yesArchiv der Pharmazie, Volume 358, Issue 5, May 2025.
The pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐dioxide class was investigated with the aim of enlarging the array of Staphylococcus aureus NorA efflux pump inhibitors. The ethidium bromide efflux assay was used as a first indication of NorA inhibition; then, the ability of compounds to synergize with ciprofloxacin (CPX) against both wild‐type and resistant ...
Giada Cernicchi   +14 more
wiley   +1 more source

Methylhydrazine Lone‐Pair Engineering for Polar Lead‐Free Perovskite Enables Self‐Powered X‐Ray Detection

open access: yesSmall Science, Volume 5, Issue 5, May 2025.
Utilizing the organic cation MHy with 2s2 lone‐pair electrons, the chiral‐polar lead‐free perovskite MHy3Bi2I9 is constructed in the famous A3Bi2I9 system. The symmetry breaking ascribes to the asymmetric transmission from MHy to the Bi2I9 inorganic skeleton through hydrogen bonding.
Ruiqing Li   +8 more
wiley   +1 more source

Hydrazine as a Reducing Agent in Catalytic Transfer Hydrogenation Processes: Up‐to‐Date Overview Approaches

open access: yesChemCatChem, Volume 17, Issue 8, April 15, 2025.
Transfer hydrogenation serves as an alternative platform to promote facile organic transformation in a selective and clean manner, due to its atomic economy, high efficiency, and sustainability. Hydrazine hydrate is one of the common reducing agents used in the selective transfer hydrogenation/reduction methodologies.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

An up‐To‐Date Review of Elesclomol and Its Nano‐Formulations in Cancer Therapy

open access: yesCancer Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background Elesclomol (ES) is a promising anticancer compound that exerts its effects through multiple mechanisms. It acts as a copper (Cu(II)) ionophore, forming an ES–Cu complex within cancer cells and inducing a novel form of cell death called cuproptosis.
Qi Wang   +3 more
wiley   +1 more source

Synthesis of Substituted Acyclic and Cyclic N‐Alkylhydrazines by Enzymatic Reductive Hydrazinations

open access: yesChemBioChem, Volume 26, Issue 4, February 16, 2025.
Imine reductases (IREDs) offer promising synthesis routes for chiral amines. We have demonstrated reductive amination of diverse carbonyls and dicarbonyls with hydrazines, catalyzed by Myxococcus stipitatus IRED. Incorporating a hydrogenase cofactor regeneration system showcases the scalability and atom‐efficiency of H2‐driven double reductive ...
Niels Borlinghaus   +3 more
wiley   +1 more source

Nitrogen-15 Magnetic Resonance Spectroscopy. XV. Natural-Abundance Spectra. Chemical Shifts of Hydrazines

open access: yes, 1972
The ^(15)N resonances of the methylhydrazines and some phenylhydrazines have been determined at the natural-abundance level of ^(15)N. The chemical shifts for the methyl compounds were interpretable in terms of deshielding α and β effects. The β shift, -
Roberts, John D., Lichter, Robert L.
core  

Spontaneous Cyclization of 2‐Methylthiosemicarbazones Yields New 1,2,4‐Triazolidine‐3‐thiones, Useful as Building Blocks for Drug Design

open access: yesChemistrySelect, Volume 10, Issue 2, January 15, 2025.
This study represents a simple and straightforward synthetic approach to the formation of new cyclic 1,2,4‐triazolidine‐3‐thione compounds. The reaction of 2‐methylthiosemicarbazide with ketones leads to 2‐methylthiosemicarbazone cyclization, yielding 1,2,4‐triazolidine‐3‐thiones. Selected compounds were tested for cytotoxicity, antimicrobial activity,
Simona Gričar   +5 more
wiley   +1 more source

Coordination compounds of boron trifluoride with methylhydrazines.

open access: yes, 1966
Boron trifluoride-ammonia, BF3• NH3, the first complex of boron trifluoride with a nitrogen pontaining base, was prepared by Gay Lussac (1). Since then many complexes of boron trifluoride with amines, amides, nitriles and nitrogen containing ...
Bhiwandker, Nutan Chandrakant.
core  

Safety of temozolomide use in adult patients with renal dysfunction. [PDF]

open access: yesJ Neurooncol, 2022
Garzio K   +5 more
europepmc   +1 more source

Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19. [PDF]

open access: yesInt J Mol Sci, 2021
Vilskersts R   +9 more
europepmc   +1 more source

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