Results 21 to 30 of about 229 (180)

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

open access: yesThe Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Synthesis and Biological Profile of Substituted Pyrrolidinyl Carboxamides for Acyl‐ACP Thioesterase Inhibition

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 12, 23 March 2026.
The work outlined herein covers a series of novel herbicidal lead structures that possess a pyrrolidinyl pyrazole carboxamide scaffold as a key structural feature, carrying further substituted benzyl side chains. Based on scaffold hopping approaches from known fungicidal and herbicidal compounds and utilizing an optimized synthetic approach, a broader ...
Elisabeth Asmus   +24 more
wiley   +1 more source

1,1-Dimethylhydrazine [PDF]

open access: yes
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) has re-evaluated the occupational exposure limit value (maximum concentration at the workplace, MAK value) of 1,1-dimethylhydrazine [57 ...
Arand, Michael   +2 more
core   +1 more source

Synthetic Strategies to Access Fluorinated Azoles

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber   +4 more
wiley   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

open access: yesChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Anticancer drugs in the aquatic environment: where should we act and is nanofiltration a solution to this problem? [PDF]

open access: yes, 2022
Anticancer drugs have been detected in hospital effluents, sewage effluents and river water samples. Due to the increasing number of cancer patients, an increase in the consumption of anticancer drugs is expected and therefore the development of ...
Cristóvão, Maria Beatriz Sá Mesquita da Silva
core  

Investigation of the Surface Reconstruction and Gas Phase Composition during Growth by MOVPE [PDF]

open access: yes, 2021
Die metallorganische Gasphasenepitaxie (metal organic vapor phase epitaxy, MOVPE) hat eine wichtige Rolle als Herstellungsmethode der III-V-Halbleitermaterialien für optoelektronische Anwendungen inne.
Maßmeyer, Oliver Peter
core   +1 more source

Sequential Optimization Approach Toward an Azapeptide‐Based SARS‐CoV‐2 Main Protease Inhibitor

open access: yesArchiv der Pharmazie, Volume 358, Issue 12, December 2025.
A series of small‐molecule azapeptides with various cysteine‐reactive electrophilic groups was designed, synthesized, and investigated for Mpro inhibition. Particularly suitable warheads were identified, and their linkage to a structurally expanded peptidomimetic scaffold afforded the potent lead compound 12, with kinac/Ki = 78,900 M–1s–1 and an ...
Rabea Voget   +9 more
wiley   +1 more source

Heterobimetallic Pd‐Ru Catalysts for the Synthesis of Functionalized Polynorbornenes via Reductive Heck/ROMP Reactions

open access: yesApplied Organometallic Chemistry, Volume 39, Issue 11, November 2025.
Monometallic and heterobimetallic Ru‐PdL complexes were synthesized and fully characterized. Their electrochemical properties were investigated by cyclic voltammetry. The Ru‐PdL complexes catalyzed the hydroarylation of NBD and the ROMP of Ph‐NBE. One complex catalyzed both reactions via tandem catalysis in one pot, converting NBD to poly (Ph‐NBE ...
Thais R. Cruz   +6 more
wiley   +1 more source

1,2-Dimethylhydrazine [PDF]

open access: yes
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) has re-evaluated the occupational exposure limit value (maximum concentration at the workplace, MAK value) of 1,2-dimethylhydrazine [540-
Arand, Michael   +2 more
core   +1 more source

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