Neurological melioidosis presenting as intracranial abscess
Melioidosis is an emerging disease in our country caused by the bacteria Burkholderia pseudomallei. Melioidosis can virtually affect any organ. It has varying clinical presentations ranging from pneumonia to fatal sepsis.
Deepak Madi +3 more
doaj +1 more source
Whole-genome sequencing of a quarter-century melioidosis outbreak in temperate Australia uncovers a region of low-prevalence endemicity [PDF]
This study was funded by the National Health and Medical Research Council via awards 1046812 and 1098337, and the Wellcome Trust Sanger Institute via award 098051. S.J.P.
Buller, Nicky +8 more
core +1 more source
Introduction: Melioidosis can have multiple organ involvement which can then mimic other infections. The aim of this study was to determine if there are any factors significantly associated with melioidosis which can inform diagnostic evaluations before
Supatjaree Chanvitan +2 more
doaj +1 more source
Melioidosis with a Pericardial Effusion, which Relapsed as a Chest Wall Abscess: A Rare Presentation [PDF]
Melioidosis, which is caused by a soil saprophyte, Burkholderia pseudomallei, is most prevalent in the south–west coast of India. Although it is frequently seen in immunocompromised patients, melioidosis can occur in apparently normal individuals ...
Rashmi Teresa Mathai K. +4 more
doaj +1 more source
Development of a prototype Lateral Flow Immunoassay (LFI) for the rapid diagnosis of melioidosis [PDF]
Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the “gold standard” for the diagnosis of melioidosis; results can take 3–7 days to ...
AuCoin, David +17 more
core +3 more sources
A Machine Learning-Based Raman Spectroscopic Assay for the Identification of Burkholderia mallei and Related Species [PDF]
Burkholderia (B.) mallei, the causative agent of glanders, and B. pseudomallei, the causative agent of melioidosis in humans and animals, are genetically closely related. The high infectious potential of both organisms, their serological cross-reactivity,
Bocklitz, Thomas +8 more
core +2 more sources
Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler +4 more
wiley +2 more sources
Melioidosis is an important cause of morbidity and mortality in northern Australia and Southeast Asia. Diagnosis is best made by isolation of Burkholderia pseudomallei from clinical specimens. A variety of clinical presentations are described, including neurologic disease.
Martin, Deuble +2 more
openaire +2 more sources
Less is more: Burkholderia pseudomallei and chronic melioidosis [PDF]
10.1128/mBio.00709 ...
Chantratita +17 more
core +1 more source
Emergence of Melioidosis in Indonesia and Today’s Challenges
A recent modeling study estimated that there could be as many as 20,000 human melioidosis cases per year in Indonesia, with around 10,000 potential deaths annually. Nonetheless, the true burden of melioidosis in Indonesia is still unknown.
Patricia M. Tauran +23 more
doaj +1 more source

