Results 31 to 40 of about 9,609 (223)

Improving the clinical recognition, prognosis, and treatment of melioidosis through epidemiology and clinical findings: The Sabah perspective.

PLoS Neglected Tropical Diseases, 2023
IntroductionMelioidosis is a deadly endemic disease in northern Australia and Southeast Asia, including Sabah, Malaysia, which is caused by the bacterium Burkholderia pseudomallei. It contributes to high fatality rates, mainly due to misdiagnosis leading
Ainulkhir Hussin, Mohd Yusof Nor Rahim, Frederick Dalusim, Muhammad Ashraf Shahidan, Sheila Nathan, Nazlina Ibrahim   +5 more
doaj   +1 more source

Melioidosis, Northeastern Brazil

, 2005
Melioidosis is a fatal bacterial infection found in many parts of the tropical belt, particularly in Southeast Asia and northern Australia. Sporadic cases of the disease have been reported previously in Central and South America.
Howard, K., Miralles, I.S., Sampson, I., O'Reilly, L., Diana Carmen Almeida de Oliveira, Timothy J.J. Inglis, Vilar, D.C.F.L., de Oliveira, D.C.A., Dina Cortez Feitosa Lima Vilar, Rolim, D.B., Ian Sampson, Inglis, T.J.J., Harnett, G., Lyn O'Reilly, Kay Howard, Dionne Bezerra Rolim, Iracema Sampaio Miralles, Sousa, A.Q., Gerry Harnett, Anastacio Queiroz Sousa   +19 more
core   +1 more source

Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen burkholderia pseudomallei K96243 [PDF]

, 2010
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease ...
Wilkinson Paul A., Dowling, Andrea J., Matthew T G Holden, Richard W. Titball, Nicholas R. Waterfield, Paul A Wilkinson, Titball, Richard W., Quail, MA, Bentley Stephen D., Holden Matthew T. G., Richard W Titball, Bentley, SD, Julia Reger, Quail, Michael A., Waterfield Nicholas R., Stephen D. Bentley, Waterfield, NR, Andrea J Dowling, Stephen D Bentley, Wilkinson, Paul A., Bentley, Stephen D., Holden, Matthew T. G., ffrench-Constant, Richard H., ffrench-Constant Richard H., ffrench-Constant, Richard, Richard H. ffrench-Constant, Paul A. Wilkinson, Matthew T. G. Holden, Michael A. Quail, Michael A Quail, Waterfield, Nicholas R., Dowling Andrea J., Reger, J, Titball Richard W., Nicholas R Waterfield, Reger, Julia, Quail Michael A., Andrea J. Dowling, Andrea J. Dowling, Richard H Ffrench-Constant, Dowling, AJ, Holden, Matthew, Wilkinson, PA, Reger Julia   +43 more
core   +1 more source

Melioidosis

Zentralblatt für Bakteriologie, 1994
Melioidosis, which is infection with the gram-negative bacterium Burkholderia pseudomallei, is an important cause of sepsis in east Asia and northern Australia. In northeastern Thailand, melioidosis accounts for 20% of all community-acquired septicaemias, and causes death in 40% of treated patients.
openaire   +4 more sources

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

The soil microorganism Bacillus amyloliquefaciens N3-8 shows potential as a biocontrol agent against the pathogen Burkholderia pseudomallei and its effect on rice plantation

Microbiology Spectrum
Burkholderia pseudomallei is a saprophytic bacterium responsible for melioidosis in humans and animals. In this study, Bacillus amyloliquefaciens N3-8 was applied as a biocontrol agent on sterile soil spiked with 107 colony-forming unit (CFU) per gram of
Chotima Potisap, Phrueksa Lawongsa, Jittima Duangsri, Júlia B. Gontijo, Surasakdi Wongratanacheewin, Jorge L. Mazza Rodrigues, Rasana W. Sermswan   +6 more
doaj   +1 more source

Melioidosis Patient Survival Correlates With Strong IFN-γ Secreting T Cell Responses Against Hcp1 and TssM

Frontiers in Immunology, 2021
Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a serious infectious disease with diverse clinical manifestations. The morbidity and mortality of melioidosis is high in Southeast Asia and no licensed vaccines currently ...
Sineenart Sengyee, Atchara Yarasai, Rachan Janon, Chumpol Morakot, Orawan Ottiwet, Lindsey K. Schmidt, T. Eoin West, T. Eoin West, T. Eoin West, Mary N. Burtnick, Mary N. Burtnick, Narisara Chantratita, Narisara Chantratita, Paul J. Brett, Paul J. Brett   +14 more
doaj   +1 more source

Melioidosis

Journal of Association of Pulmonologist of Tamil Nadu, 2023
Melioidosis is caused by Burkholderia pseudomallei, which is normally present in soil, endemic in the tropical and subtropical regions. It has a varied clinical presentation from presenting with acute symptoms and sepsis and rarely presenting as subacute to chronic disease.
H Ria Lawrence, Gayathri Anur Ramakrishnan   +1 more
openaire   +2 more sources

Low-dose exposure of C57BL/6 mice to burkholderia pseudomallei mimics chronic human melioidosis.

, 2011
Burkholderia pseudomallei is the etiological agent of human melioidosis, a disease with a broad spectrum of clinical manifestations ranging from fatal septicemia to chronic localized infection or asymptomatic latent infection.
Patel, Natasha, Richard W. Titball, Prior, J, Salguero, FJ, Laura Conejero, Oberdorf, Sara, de Reynal, M, Titball, RW, Francisco J. Salguero, Gregory J. Bancroft, Joanne Prior, Prior, Joanne, Natasha Patel, Philip L. Felgner, Oberdorf, S, Conejero, L, Titball, Richard W, Felgner, Philip L, Conejero, Laura, Salguero, Francisco J, Felgner, PL, Bancroft, GJ, Melanie de Reynal, Sara Oberdorf, Bancroft, Gregory J, de Reynal, Melanie, Patel, N   +26 more
core   +1 more source

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]

, 2014
UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Richard W. Titball, Titball, Richard W., Lim, Jiali, Wren, Brendan W, Guerra-Assunção, José Afonso, Tan, Patrick B.O., Madeleine G. Moule, Mitali Sarkar-Tyson, Moule, Madeleine G.; id_orcid, Hemsley, Claudia M, Wren, Brendan W., Brendan W. Wren, Moule, Madeleine G, Patrick B. O. Tan, José Afonso Guerra-Assunção, Clark, Taane G., Qihui Seet, Titball, Richard W, Jiali Lim, Seet, Qihui, Tan, Patrick BO, Sarkar-Tyson, Mitali, Cuccui, Jon, Taane G. Clark, Claudia M. Hemsley, Clark, Taane G, Hemsley, Claudia M., Jon Cuccui   +27 more
core   +1 more source