Results 31 to 40 of about 6,424 (173)
Frontiers in Immunology, 2021 Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a serious infectious disease with diverse clinical manifestations. The morbidity and mortality of melioidosis is high in Southeast Asia and no licensed vaccines currently ...
Sineenart Sengyee +14 more
doaj +1 more source
Australian Veterinary Journal, EarlyView.Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee +6 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.Dicentrine, an aporphine alkaloid, exhibits potent in vitro antileishmanial activity against Leishmania species with high selectivity and low macrophage cytotoxicity. Mechanistic studies reveal that the compound triggers parasite death possibly by inducing mitochondrial membrane disruption and oxidative stress.
Camila S. de Freitas +9 more
wiley +1 more source
Zentralblatt für Bakteriologie, 1994 Melioidosis, which is infection with the gram-negative bacterium Burkholderia pseudomallei, is an important cause of sepsis in east Asia and northern Australia. In northeastern Thailand, melioidosis accounts for 20% of all community-acquired septicaemias, and causes death in 40% of treated patients.
openaire +4 more sources
Journal of Association of Pulmonologist of Tamil Nadu, 2023 Melioidosis is caused by Burkholderia pseudomallei, which is normally present in soil, endemic in the tropical and subtropical regions. It has a varied clinical presentation from presenting with acute symptoms and sepsis and rarely presenting as subacute to chronic disease.
H Ria Lawrence +1 more
openaire +2 more sources
Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler +4 more
wiley +2 more sources
Melioidosis in the head-and-neck region
Journal of Clinical and Scientific ResearchBurkholderia pseudomallei, an environmental saprophyte, causes an infection that results in melioidosis. A high case-fatality rate is linked to it. Melioidosis is becoming an increasingly global infection. It can present a wide spectrum of manifestations
Santosh Kumar Swain, Vasudha Singh
doaj +1 more source
Respirology Case Reports, Volume 14, Issue 8, August 2026.Dyspnoea, cough and weight loss initially suggested thoracic malignancy. CT thorax–abdomen demonstrated a large right subcapsular pyogenic liver abscess with contiguous non‐fistulous transdiaphragmatic spread causing lung abscess and pleural empyema. Image‐guided liver abscess drainage and prolonged antimicrobial therapy led to sustained clinical and ...
Zhong Xhen Khor +4 more
wiley +1 more source
Melioidosis in the remote Katherine region of northern Australia.
PLoS Neglected Tropical Diseases, 2022 Melioidosis is endemic in the remote Katherine region of northern Australia. In a population with high rates of chronic disease, social inequities, and extreme remoteness, the impact of melioidosis is exacerbated by severe weather events and ...
Kay Hodgetts +9 more
doaj +1 more source
Emergency Medicine Australasia, Volume 38, Issue 4, August 2026.ABSTRACT Objective Townsville, North Queensland, experienced record rainfall in the 2024–2025 wet season with an associated surge in the number of patients with melioidosis. A large proportion presented to the Townsville University Hospital (TUH) emergency department (ED), presenting an opportunity to assess the surge from an ED perspective.
Colin Banks +7 more
wiley +1 more source