Evaluation of β-cyclodextrin-modified gemini surfactant-based delivery systems in melanoma models
Deborah Michel,1 Waleed Mohammed-Saeid,1 Heather Getson,1 Caitlin Roy,1 Masoomeh Poorghorban,1 Jackson M Chitanda,2 Ronald Verrall,2 Ildiko Badea1 1Drug Design and Discovery Research Group, College of Pharmacy and Nutrition, 2Department of Chemistry ...
Michel D +7 more
doaj
Intraperitoneal chemotherapy with cisplatin and melphalan.
Cisplatin and melphalan given ip exert a synergistic therapeutic effect against ascitic P388 leukemia in mice and have different dose-limiting toxic effects as well as favorable pharmacokinetic characteristics in ip phase I studies. We gave a total of 98
Sculier, Jean-Paul +9 more
core
New melphalan derivatives for the treatment of retinoblastoma in combination with thermotherapy
Of the different modalities used to treat retinoblastoma, a chemothermotherapeutic regimen combining carboplatin and thermotherapy (also termed focal therapy), and the application of melphalan as a monotherapy, are particularly successful.
Munier, Francis L +22 more
core +1 more source
Modulation of miR-204 and miR-375 Expression by Flavonoid Chrysin Treatment During Melphalan-Induced Histopathological Damage in Adult Rat Skin and Hair Tissue. [PDF]
Moghimian M +4 more
europepmc +1 more source
Melphalan and Curcumin Induce Apoptosis in Retinoblastoma Cells Associated with STAT3 Signaling Modulation. [PDF]
Duman E +3 more
europepmc +1 more source
Plenary Abstracts Session & Oral Presentations
HemaSphere, Volume 10, Issue S1, June 2026.
wiley +1 more source
Mind the Gap: eGFR Discordancy and Melphalan Toxicity in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant. [PDF]
Aklilu AM, Shirali AC.
europepmc +1 more source
Preclinical Studies of the Melphalan Prodrug J1 for Cancer Therapy [Elektronisk resurs]
J1 (L-melphalanyl-L-p-fluorophenylalanyl ethyl ester) is a dipeptide derivative of the alkylating agent melphalan with increased cytotoxicity. In this thesis the preclinical pharmacology of J1 has been characterized.Our results show that J1 rapidly ...
Larsson, Rolf +3 more
core
Immunoembolization in liver-predominant metastatic uveal melanoma: a single-center retrospective analysis. [PDF]
Morecroft R +8 more
europepmc +1 more source

