Results 31 to 40 of about 211,880 (179)

Enhancing dissolution of artesunate from immediate release tablets using a green granulation technique

Archives of Pharmaceutical Sciences Ain Shams University, 2019
Artesunate is a poorly soluble drug and liable to aqueous hydrolysis. This study aims to formulate Artesunate as an immediate release tablet through optimization of the melt granulation technique to improve the dissolution of the drug.
Akram ahmad Bashir , sameh abd-elhamid, Alia Badawi, Ahmed S. Geneidi   +3 more
doaj   +1 more source

Effects of Humidity on the Dissolution Profiles of Controlled Release Theophylline Matrix Tablets Containing Release Enhancers Prepared By Melt Granulation and Coacervation Techniques

Journal of Applied Sciences and Environmental Management, 2020
The quantity of moisture present in tablets plays a major role in influencing the physical/chemical properties of tablets especially dissolution profiles.
J.A. Avbunudiogba
doaj   +1 more source

The effect of binder concentration in fluidized-bed granulation: Transition between wet and melt granulation [PDF]

, 2018
According to the binder nature, fluidized-bed granulation (FBG) is usually classified as wet or melt granulation. In particular, the industrial urea granulation performed in fluidized beds, is often called “melt granulation” because a highly concentrated
Diego Bertín, Piña, Juliana, Ivana M. Cotabarren, Veliz Moraga, Sussy Ximena, Bertin, Diego Esteban, Juliana Piña, Cotabarren, Ivana María, Sussy Veliz Moraga, Bucala, Veronica, Verónica Bucalá   +9 more
core   +1 more source

Glyceryl Laurate Tablets: Effect of the Excipients and Granule Size on the Tablet Quality

European Pharmaceutical Journal, 2023
Glyceryl laurate (GL) is a natural or synthetic surfactant with antiviral and antimicrobial activity and is not only effective in common colds or flu, but also against swine flu, herpes simplex, shingles, or chronic fatigue.
Špaglová M., Papadakos M., Čuchorová M., Krchňák D., Šimunková V., Matušová D.   +5 more
doaj   +1 more source

Wet granulation in laboratory scale high shear mixers: Effect of binder properties [PDF]

, 2011
The effect of binder properties on torque curves, granule growth kinetics, wet mass consistency and dry granule strength has been investigated in this study.
Hemati, Mehrdji, M. Hemati, Oulahna, Driss, T.M. Chitu, D. Oulahna, Chitu, Toma Mihai   +5 more
core   +1 more source

The impact of hot melt granulation method on propranolol hydrochloride physicochemical properties [PDF]

, 2005
Hot melt granulation is based on agglomeration by use of thermoplastic binder material that is solid at room temperature and softens and melts at higher temperature. By selecting a binder that is insoluble in water, melt granulation is a way of producing
Nugrahani, Ilma; Faculty of Pharmacy University of Pancasila Jakarta Indonesia, Rahmat, Hasan; Department of Pharmacy Faculty of Mathematics and Natural Sciences, Depok Indonesia, Djajadisastra, Joshita; Department of Pharmacy Faculty of Mathematics and Natural Sciences, Depok Indonesia   +2 more
core   +1 more source

Evaluation of gum mastic (Pistacia lentiscus) as a microencapsulating and matrix forming material for sustained drug release

Asian Journal of Pharmaceutical Sciences, 2017
In this study, a natural gum mastic was evaluated as a microencapsulating and matrix-forming material for sustained drug release. Mastic was characterized for its physicochemical properties.
Dinesh M. Morkhade
doaj   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Fluidized Hot Melt Granulation: Influence of Process and Formulation Parameters

, 2010
Introduction: Hot-melt granulation techniques have received increasing attention due to the significant advantages compared to the conventional granulation methods.
I. MAŠIĆ, J. PAROJČIĆ, Z. ĐURIĆ, A. STOJKOVIĆ   +3 more
core   +1 more source

Characterization and Prediction of the Non-Bonded Molecular Interactions between Racemic Ibuprofen and α-Lactose Monohydrate Crystals Produced from Melt Granulation and Slow Evaporation Crystallization

Indonesian Journal of Chemistry, 2020
Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition.
Zulfahmi Lukman, Nornizar Anuar, Noor Fitrah Abu Bakar, Norazah Abdul Rahman   +3 more
doaj   +1 more source