Dilatancy, Jamming, and the Physics of Granulation [PDF]
, 2004 Granulation is a process whereby a dense colloidal suspension is converted into pasty granules (surrounded by air) by application of shear. Central to the stability of the granules is the capillary force arising from the interfacial tension between ...
Bibette J +19 more
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Rapid Preparation of Spherical Granules via the Melt Centrifugal Atomization Technique
Pharmaceutics, 2019 Granules with superior fluidity and low moisture absorption are ideal for tableting and capsule filling. Melt granulation as a solvent-free technology has attracted increasing interest for the granulation of moisture-sensitive drugs. The objective of the
Yan Yang +5 more
doaj +1 more source
Archives of Pharmaceutical Sciences Ain Shams University, 2019 Artesunate is a poorly soluble drug and liable to aqueous hydrolysis. This study aims to formulate Artesunate as an immediate release tablet through optimization of the melt granulation technique to improve the dissolution of the drug.
Akram ahmad Bashir +3 more
doaj +1 more source
Journal of Applied Sciences and Environmental Management, 2020 The quantity of moisture present in tablets plays a major role in influencing the physical/chemical properties of tablets especially dissolution profiles.
J.A. Avbunudiogba
doaj +1 more source
Использование золошлаковых материалов теплоэнергетики в строительных материалах [PDF]
, 2015 The possible trends to improve the building-technical properties of dry ashes characteristics formed as a result of solid fuel combustion at thermal power stations are presented.
Kapustin, A. F. +5 more
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Glyceryl Laurate Tablets: Effect of the Excipients and Granule Size on the Tablet Quality
European Pharmaceutical Journal, 2023 Glyceryl laurate (GL) is a natural or synthetic surfactant with antiviral and antimicrobial activity and is not only effective in common colds or flu, but also against swine flu, herpes simplex, shingles, or chronic fatigue.
Špaglová M. +5 more
doaj +1 more source
A quality by design (QbD) twin—screw extrusion wet granulation approach for processing water insoluble drugs [PDF]
, 2017 In this study, a Quality by Design (QbD) approach was used to identify the effect of formulation parameters in a twin screw wet extrusion granulation process for the manufacturing of ibuprofen (IBU) granules with increased dissolution rates. A fractional
Dey, Tumpa +5 more
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Evaluation of the compression properties of co-processed paracetamol, gelatin and microcrystalline cellulose formulation prepared via melt-in agglomeration [PDF]
Trends in Pharmaceutical Sciences, 2022 Co-processing techniques have been used to modify the properties of dosage forms. The aim of this study is to evaluate the granules and tablet properties of co-processed paracetamol, gelatin and microcrystalline cellulose.
Didacus Nnamani, Sylvester Eraga
doaj +1 more source
Continuous manufacturing via hot-melt extrusion and scale up: regulatory matters [PDF]
, 2017 Currently, because globalization, the pharmaceutical industry is facing enormous challenges to comply with regulatory matters. Reduced patent life and overall decreased profitability of newly discovered drugs are also forcing the pharmaceutical industry ...
Abboud +86 more
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Impact of the manufacturing technique on the dissolution-enhancement functionality of PEG4000 in Cilostazol tablets [PDF]
Pharmacia, 2021 Cilostazol was selected as poorly-soluble model drug to investigate the impact of the manufacturing method on the excipient functionality of PEG4000 at various levels.
Obada Sawafta +4 more
doaj +3 more sources