Results 41 to 50 of about 8,552 (232)

Preparation and characterisation of ibuprofen–poloxamer 188 granules obtained by melt granulation

European Journal of Pharmaceutical Sciences, 2002
The aim of this study was to prepare, by melt granulation, granules containing ibuprofen as a poorly water soluble model drug in order to improve its dissolution rate and its availability; lactose as a diluent and poloxamer 188 (Lutrol F68), as a new meltable hydrophilic binder, were used.
Nadia, Passerini, Beatrice, Albertini, Marisa L, González-Rodríguez, Cristina, Cavallari, Lorenzo, Rodriguez   +4 more
openaire   +2 more sources

Evaluation of gum mastic (Pistacia lentiscus) as a microencapsulating and matrix forming material for sustained drug release

Asian Journal of Pharmaceutical Sciences, 2017
In this study, a natural gum mastic was evaluated as a microencapsulating and matrix-forming material for sustained drug release. Mastic was characterized for its physicochemical properties.
Dinesh M. Morkhade
doaj   +1 more source

Characterization and Prediction of the Non-Bonded Molecular Interactions between Racemic Ibuprofen and α-Lactose Monohydrate Crystals Produced from Melt Granulation and Slow Evaporation Crystallization

Indonesian Journal of Chemistry, 2020
Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition.
Zulfahmi Lukman, Nornizar Anuar, Noor Fitrah Abu Bakar, Norazah Abdul Rahman   +3 more
doaj   +1 more source

Influence of fill factor variation in high shear granulation on the post granulation processes: Compression and tablet properties [PDF]

, 2014
This paper describes an investigation of the effect of fill factor on the compaction behaviour of the granules during tabletting and hence mechanical properties of tablets formed.
A.D. Salman, Adams, Ameye, Bock, Broadbent, C. Mangwandi, Campisi, Chan, Chantraine, Chantraine, Chantraine, Cruz, Darelius, Dévay, E.P., Fell, Franch-Lage, Hassanpour, Heng, Iveson, Johansson, Landin, Landin, Langenbucher, M.J. Adams, M.J. Hounslow, Mangwandi, Mangwandi, Mangwandi, Mangwandi, Mangwandi, Mangwandi, Mangwandi, Moes, Mort, Mort, Pontier, Quaicoe, Rahmanian, Santos, Schaefer, Smith, Tereshita, Thies, Vajna, Viana, Wu   +46 more
core   +1 more source

Melt-spun bioactive sutures containing nanohybrids for local delivery of anti-inflammatory drugs. [PDF]

, 2014
In this work, a novel concept is introduced in drug-eluting fibres to ensure a good control of drug delivery features and wide applicability to different bioactive compounds. Composite bioactive sutures based on fibre grade poly(ε-caprolactone) (PCL) and
Acierno S, ACIERNO, DOMENICO, Bolognese A, CALIFANO, LUIGI, CALIGNANO, ANTONIO, CATANZANO, OVIDIO, Cervasio M, DEL BASSO DE CARO, MARIALAURA, MARENZI, GAETANO, QUAGLIA, FABIANA, Russo P, SAMMARTINO, GILBERTO   +11 more
core   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

Advanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source

Essential work of fracture of poly(ϵ-caprolactone)/boehmite alumina nanocomposites: Effect of surface coating [PDF]

, 2013
The essential work of fracture (EWF) approach has been adopted to reveal the effect of nanofillers on the toughness of poly(ε-caprolactone)/boehmite alumina (PCL/BA) nanocomposites.
Bárány, Cotterell, Crescenzi, Ferrer-Balas, Ferrer-Balas, Gámez-Pérez, Karger-Kocsis, Karger-Kocsis, Khumalo, Khumalo, Martinez, Pegoretti, Streller, Tuba, Tuba, Tuba, Tuba, Tuba, Tuba, Wang, Williams, Wong   +21 more
core   +1 more source

Hybrid Magnetoactive Soft Elastomers: Material Development Toward Application in Diaphragm Pumps

Advanced Materials Technologies, EarlyView.
Hybrid magnetoactive soft elastomeric membranes are developed by combining two different types of magnetic particles. The membranes exhibit distinct mechanical, magnetic and thermal properties owing to the unique characteristics of the two magnetic particles.
Somashree Mondal, Paweł Orkisz, Bogdan Sapiński, Ralph Spolenak, Frank Clemens   +4 more
wiley   +1 more source

Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms

Intelligent Pharmacy
This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation.
Anil Kumar Vadaga, Sai Shashank Gudla, Gnanendra Sai Kumar Nareboina, Hymavathi Gubbala, Bhuvaneswari Golla   +4 more
doaj   +1 more source

Application of multivariate techniques in the evaluation of melt granulation products

Brazilian Journal of Pharmaceutical Sciences, 2011
In this work, principal component analysis and cluster analysis were applied as helping tools to extract useful information in the development of formulations and manufacturing processes of melt granulates.
Ana Teresa Ochoa Andrade
doaj   +1 more source