Results 161 to 170 of about 10,108,350 (409)
Akademik İncelemeler DergisiThe European Union (EU) has been challenged by several crises lately. In addition to Brexit, the Euro crisis, and the migration crisis; global issues such as the coronavirus pandemic and the Russian attack on Ukraine affected the EU. The migration crisis,
Buket Ökten Sipahioğlu
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Comparative analysis of working conditions in the European Union Member States [PDF]
This paper presents the main findings of the author’s study of statistics as well as Eu-ropean surveys on working conditions. Such solutions enabled to compare the data and make the results more reliable.
Wach, Krzysztof
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Social Justice in the EU – Index Report 2017 Social Inclusion Monitor Europe. Bertelsmann Stiftung Social Inclusion Monitor Europe 2017 [PDF]
, 2017 1. Europe is recovering not only economically, but also in the domain of social justice After years of downward movement, an upward trend in the domain of social justice is evident in the broad majority of EU member states.
Christof Schiller, Christof Schiller +3 more
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Spatial tax competition in the EU15. [PDF]
Tax competition in the European Union is ¯erce. Especially since the en-try of the new member States, tax reforms in the "old" Europe are frequent.In this paper we formally test the presence of strategic tax setting in the oldEU14 as a reaction to the ...
Crabbé, Karen, Vandenbussche, Hylke
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The Compliance Problem in the European Union. EIPAScope 2006(1):pp. 12-18 [PDF]
, 2006 The European Union has an implementation “deficit”. The measures adopted by the EU are not always applied – or are not applied correctly – by all Member States. This is a serious problem.
Nicolaides, Phedon, Oberg, Helen.
core
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Participation of representatives of ICSTI member states in SPIEF-2022
, 2022 article Editorial
openalex +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source