Results 41 to 50 of about 5,646,580 (347)

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

Nature Communications, 2016
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts ...
Yijian Rao, Marco G. Perna, Benjamin Hofmann, Viola Beier, Thomas Wollert   +4 more
doaj   +1 more source

Membrane fouling monitoring by 3ω sensing

Scientific Reports, 2023
Membrane fouling significantly reduces membrane permeability, leading to higher operational expenses. In situ monitoring of membrane fouling can potentially be used to reduce operation cost by optimizing operational parameters and cleaning conditions. In
Mads Koustrup Jørgensen, Frederikke Kildeberg Paulsen, Anders Bentien, Astrid Ræbild Kjul, Maiken Poulsen, Louise Mailund Mikkelsen, Nikitha Thavaneswaran, Simon Abildgaard Hansen, Pernille Krogsager Jensen, Jacob Andersen, David N. Østedgaard-Munck, Jan Dimon Bendtsen, Morten Lykkegaard Christensen   +12 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Ionic Liquid Confined in Mesoporous Polymer Membrane with Improved Stability for CO2/N2 Separation

Nanomaterials, 2017
Supported ionic liquid membranes (SILMs) have a promising prospect of application in flue gas separation, owing to its high permeability and selectivity of CO2.
Ming Tan, Jingting Lu, Yang Zhang, Heqing Jiang   +3 more
doaj   +1 more source

The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes

Communications Biology, 2023
In arterial myocytes, the canonical function of voltage-gated CaV1.2 and KV2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively.
Collin Matsumoto, Samantha C. O’Dwyer, Declan Manning, Gonzalo Hernandez-Hernandez, Paula Rhana, Zhihui Fong, Daisuke Sato, Colleen E. Clancy, Nicholas C. Vierra, James S. Trimmer, L. Fernando Santana   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Peptide‐Derived Aggregation‐Induced Emission Nanobioprobe: Unlocking Selective Detection of Fusobacterium nucleatum and Noninvasive Screening of Colorectal Cancer

Aggregate
Colorectal cancer (CRC) screening and early diagnosis is an effective strategy for reducing CRC mortality. However, the current detection methods involve exorbitant costs and complex procedures, which are inconvenient for large‐scale screening. Given its
Hongyu Liu, Tengling Wu, Yunjian Yu, Youtao Xin, Hegang Lu, Shengke Zhao, Meihui Su, Lu Ga, Alideertu Dong, Mahmoud Elsabahy, Hui Gao   +10 more
doaj   +1 more source

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

Molecular Systems Biology, 2012
The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia, Germaine Goh, Victor Racine, Susanne Ng, Pankaj Kumar, Frederic Bard   +5 more
doaj   +1 more source

Modelling of Ion Transport in Electromembrane Systems: Impacts of Membrane Bulk and Surface Heterogeneity

Applied Sciences, 2018
Artificial charged membranes, similar to the biological membranes, are self-assembled nanostructured materials constructed from macromolecules.
Victor Nikonenko, Andrey Nebavsky, Semyon Mareev, Anna Kovalenko, Mahamet Urtenov, Gerald Pourcelly   +5 more
doaj   +1 more source

Reactive Flame-Retardant Cotton Fabric Coating: Combustion Behavior, Durability, and Enhanced Retardant Mechanism with Ion Transfer

Nanomaterials, 2022
In recent years, we have witnessed numerous indoor fires caused by the flammable properties of cotton. Flame-retardant cotton deserves our attention. A novel boric acid and diethylenetriaminepenta (methylene-phosphonic acid) (DTPMPA) ammonium salt-based ...
Wenju Zhu, Qing Wang, Mingyang Yang, Minjing Li, Chunming Zheng, Dongxiang Li, Xiaohan Zhang, Bowen Cheng, Zhao Dai   +8 more
doaj   +1 more source