Results 41 to 50 of about 77,483 (239)
Dynamics of Nonequilibrium Membrane Bud Formation [PDF]
Physical Review Letters, 2004 The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or membrane curvature, depending upon the spatial extent of the perturbation.
openaire +4 more sources
Virus Entry, Assembly, Budding, and Membrane Rafts [PDF]
Microbiology and Molecular Biology Reviews, 2003 SUMMARY As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries for completion of their replication cycle. The recent discovery of the heterogeneous distribution of the various lipids within cell membranes has led to the proposal that sphingolipids and cholesterol tend to segregate in ...
Nathalie, Chazal, Denis, Gerlier
openaire +2 more sources
The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding. [PDF]
PLoS Pathogens, 2016 HIV virions assemble on the plasma membrane and bud out of infected cells using interactions with endosomal sorting complexes required for transport (ESCRTs). HIV protease activation is essential for maturation and infectivity of progeny virions, however,
Mourad Bendjennat, Saveez Saffarian
doaj +1 more source
Membrane Remodeling by Arc/Arg3.1
Frontiers in Molecular Biosciences, 2021 The activity-regulated cytoskeletal-associated protein (Arc, also known as Arg3.1) is an immediate early gene product induced by activity/experience and required for multiple modes of synaptic plasticity.
Per Niklas Hedde +7 more
doaj +1 more source
Budding of enveloped viruses from the plasma membrane [PDF]
BioEssays, 1997 AbstractMany enveloped viruses are released from infected cells by maturing and budding at the plasma membrane. During this process, viral core components are incorporated into membrane vesicles that contain viral transmembrane proteins, termed ‘spike’ proteins.
T L, Cadd, U, Skoging, P, Liljeström
openaire +2 more sources
Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis. [PDF]
PLoS ONE, 2017 In hepatitis C virus (HCV) polyprotein sequence, core protein terminates with E1 envelope signal peptide. Cleavage by signal peptidase (SP) separates E1 from the complete form of core protein, anchored in the endoplasmic reticulum (ER) membrane by the ...
Véronique Pène +4 more
doaj +1 more source
Dissipative Particle Dynamics Simulations for Shape Change of Growing Lipid Bilayer Vesicles
Life, 2023 The characteristic shape changes observed in the growth and division of L-form cells have been explained by several theoretical studies and simulations using a vesicle model in which the membrane area increases with time.
Hiromi Mitsuhashi +3 more
doaj +1 more source
Budding of crystalline domains in fluid membranes
Physical Review E, 2003 Crystalline domains embedded in fluid membrane vesicles are studied by Monte Carlo simulations of dynamically triangulated surfaces and by scaling arguments. A budding transition from a caplike state to a budded shape is observed for increasing spontaneous curvature C0 of the crystalline domain as well as increasing line tension lambda. The location of
Kohyama, T., Kroll, D. M., Gompper, G.
openaire +3 more sources
Budding and vesiculation induced by conical membrane inclusions [PDF]
Physical Review E, 2009 Conical inclusions in a lipid bilayer generate an overall spontaneous curvature of the membrane that depends on concentration and geometry of the inclusions. Examples are integral and attached membrane proteins, viruses, and lipid domains. We propose an analytical model to study budding and vesiculation of the lipid bilayer membrane, which is based on ...
Auth, T., Gompper, G.
openaire +4 more sources
Gaussian curvature and the budding kinetics of enveloped viruses.
PLoS Computational Biology, 2019 The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell.
Sanjay Dharmavaram +4 more
doaj +1 more source