Results 51 to 60 of about 136,075 (281)
The role of traction in membrane curvature generation. [PDF]
, 2018 Curvature of biological membranes can be generated by a variety of molecular mechanisms including protein scaffolding, compositional heterogeneity, and cytoskeletal forces.
Alimohamadi, H +4 more
core +1 more source
Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis. [PDF]
PLoS ONE, 2017 In hepatitis C virus (HCV) polyprotein sequence, core protein terminates with E1 envelope signal peptide. Cleavage by signal peptidase (SP) separates E1 from the complete form of core protein, anchored in the endoplasmic reticulum (ER) membrane by the ...
Véronique Pène +4 more
doaj +1 more source
Dissipative Particle Dynamics Simulations for Shape Change of Growing Lipid Bilayer Vesicles
Life, 2023 The characteristic shape changes observed in the growth and division of L-form cells have been explained by several theoretical studies and simulations using a vesicle model in which the membrane area increases with time.
Hiromi Mitsuhashi +3 more
doaj +1 more source
ENTH/ANTH proteins and clathrin-mediated membrane budding [PDF]
Journal of Cell Science, 2004 The epsin N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. Structural analyses and ligand-binding studies have shown that a set of proteins previously designated as harboring an ENTH domain in fact contain a highly similar, yet unique module ...
Legendre-Guillemin, Valérie +4 more
openaire +3 more sources
Reconstituting ring-rafts in bud-mimicking topography of model membranes. [PDF]
, 2014 During vesicular trafficking and release of enveloped viruses, the budding and fission processes dynamically remodel the donor cell membrane in a protein- or a lipid-mediated manner.
Jeon, Noo Li +11 more
core +2 more sources
Gaussian curvature and the budding kinetics of enveloped viruses.
PLoS Computational Biology, 2019 The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell.
Sanjay Dharmavaram +4 more
doaj +1 more source
Mechanism of membrane tube formation induced by adhesive nanocomponents
, 2012 We report numerical simulations of membrane tubulation driven by large colloidal particles. Using Monte Carlo simulations we study how the process depends on particle size, concentration and binding strength, and present accurate free energy calculations
A. H. Bahrami +3 more
core +1 more source
Arenavirus budding resulting from viral-protein-associated cell membrane curvature [PDF]
, 2013 Viral replication occurs within cells, with release (and onward infection) primarily achieved through two alternative mechanisms: lysis, in which virions emerge as the infected cell dies and bursts open; or budding, in which virions emerge gradually from
Abelson HT +18 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Eukaryotic-Like Virus Budding in
mBio, 2016 Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored.
Emmanuelle R. J. Quemin +5 more
doaj +1 more source