Results 51 to 60 of about 1,114,517 (249)

Bud-Neck Scaffolding as a Possible Driving Force in ESCRT-Induced Membrane Budding [PDF]

Biophysical Journal, 2015
Membrane budding is essential for processes such as protein sorting and transport. Recent experimental results with ESCRT proteins reveal a novel budding mechanism, with proteins emerging in bud necks but separated from the entire bud surface.
Mercker, Moritz, Marciniak-Czochra, Anna
openaire   +2 more sources

Membrane budding is a major mechanism of in vivo platelet biogenesis [PDF]

Journal of Experimental Medicine, 2020
How platelets are produced by megakaryocytes in vivo remains controversial despite more than a century of investigation. Megakaryocytes readily produce proplatelet structures in vitro; however, visualization of platelet release from proplatelets in vivo has remained elusive.
Kathryn S. Potts, Alison Farley, Caleb A. Dawson, Joel Rimes, Christine Biben, Carolyn de Graaf, Margaret A. Potts, Olivia J. Stonehouse, Amandine Carmagnac, Pradnya Gangatirkar, Emma C. Josefsson, Casey Anttila, Daniela Amann-Zalcenstein, Shalin Naik, Warren S. Alexander, Douglas J. Hilton, Edwin D. Hawkins, Samir Taoudi   +17 more
openaire   +3 more sources

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Langsley, G, Bernardo J. Foth, Ferguson, D.J. P., Ferguson, DJ, Markus Meissner, David J. P. Ferguson, Foth, B.J., Carolina Agop-Nersesian, Langsley, G., Agop-Nersesian, C, Meissner, M, Saskia Egarter, Meissner, M., Egarter, S., Sibley, L.D., Egarter, S, Bernardo J Foth, Gordon Langsley, Agop-Nersesian, C., David J P Ferguson, Foth, BJ   +20 more
core   +1 more source

The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets [PDF]

, 2016
Peptidoglycan is the major component of the cell envelope of virtually all bacteria. It has structural roles and acts as a selective sieve for molecules from the outer environment. Peptidoglycan synthesis is therefore one of the most important biogenesis
Eefjan Breukink, Liu, Yao, Breukink, Eefjan, Yao Liu, Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics   +5 more
core   +1 more source

Gaussian curvature and the budding kinetics of enveloped viruses.

PLoS Computational Biology, 2019
The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell.
Sanjay Dharmavaram, Selene Baochen She, Guillermo Lázaro, Michael Francis Hagan, Robijn Bruinsma   +4 more
doaj   +1 more source

How to halve ploidy : lessons from budding yeast meiosis [PDF]

, 2012
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Kerr, Gary W., Kerr, Gary, Sarkar, Sourav, Arumugam, Prakash   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Eukaryotic-Like Virus Budding in Archaea

mBio, 2016
Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored.
Emmanuelle R. J. Quemin, Petr Chlanda, Martin Sachse, Patrick Forterre, David Prangishvili, Mart Krupovic   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The universal suppressor mutation restores membrane budding defects in the HSV-1 nuclear egress complex by stabilizing the oligomeric lattice.

PLoS Pathogens
Nuclear egress is an essential process in herpesvirus replication whereby nascent capsids translocate from the nucleus to the cytoplasm. This initial step of nuclear egress-budding at the inner nuclear membrane-is coordinated by the nuclear egress ...
Elizabeth B Draganova, Hui Wang, Melanie Wu, Shiqing Liao, Amber Vu, Gonzalo L Gonzalez-Del Pino, Z Hong Zhou, Richard J Roller, Ekaterina E Heldwein   +8 more
doaj   +1 more source