Results 71 to 80 of about 136,075 (281)
, 2012 We study the shapes of pored membranes within the framework of the Helfrich theory under the constraints of fixed area and pore size. We show that the mean curvature term leads to a budding- like structure, while the Gaussian curvature term tends to ...
de la Cruz, Monica Olvera +3 more
core +1 more source
Domain-induced budding of fluid membranes
Biophysical Journal, 1993 Domains within fluid membranes grow by the aggregation of molecules which diffuse laterally within the membrane matrix. A simple theoretical model is introduced which predicts that a flat or weakly curved domain becomes unstable at a certain limiting size and then undergoes a budding or invagination process.
openaire +3 more sources
Advanced Functional Materials, EarlyView.This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
A novel minimal in vitro system for analyzing HIV-1 Gag mediated budding
, 2014 A biomimetic minimalist model membrane was used to study the mechanism and kinetics of cell-free in vitro HIV-1 Gag budding from a giant unilamellar vesicle (GUV).
Gill, Sarjeet +7 more
core +1 more source
Advanced Functional Materials, EarlyView.Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash +10 more
wiley +1 more source
Viruses, 2015 Herpes simplex virus 1 (HSV-1) capsids are assembled in the nucleus bud at the inner nuclear membrane into the perinuclear space, acquiring envelope and tegument. In theory, these virions are de-enveloped by fusion of the envelope with the outer nuclear
Peter Wild +6 more
doaj +1 more source
General neck condition for the limit shape of budding vesicles
, 2017 The shape equation and linking conditions for a vesicle with two-phase domains are derived. We refine the conjecture on the general neck condition for the limit shape of a budding vesicle proposed by J\"{u}licher and Lipowsky [Phys. Rev. Lett. \textbf{70}
Du, Qiang, Tu, Z. C., Yang, Pan
core +1 more source
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Membrane curvature sensing and symmetry breaking of the M2 proton channel from Influenza A
eLifeThe M2 proton channel aids in the exit of mature influenza viral particles from the host plasma membrane through its ability to stabilize regions of high negative Gaussian curvature (NGC) that occur at the neck of budding virions.
James Lincoff +4 more
doaj +1 more source
Diverse plasma membrane protrusions act as platforms for extracellular vesicle shedding
Journal of Extracellular Vesicles, 2021 Plasma membrane curvature is an important factor in the regulation of cellular phenotype and is critical for various cellular activities including the shedding of extracellular vesicles (EV).
Kirsi Rilla
doaj +1 more source