Results 81 to 90 of about 1,114,517 (249)
Advanced ScienceRadiotherapy failure often arises from tumor repopulation by treatment‐resistant cancer cells. Following irradiation, cancer cells can undergo endoreplication to form polyploid giant cancer cells (PGCCs)—radiation‐persistent cells capable of generating ...
Zheng Deng +20 more
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Membrane curvature sensing and symmetry breaking of the M2 proton channel from Influenza A
eLifeThe M2 proton channel aids in the exit of mature influenza viral particles from the host plasma membrane through its ability to stabilize regions of high negative Gaussian curvature (NGC) that occur at the neck of budding virions.
James Lincoff +4 more
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Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Mps2 links Csm4 and Mps3 to form a telomere-associated LINC complex in budding yeast
Life Science Alliance, 2020 The canonical LINC complex is composed of two different transmembrane proteins; this work reveals the heterotrimeric composition of the telomere-associated LINC complex in budding yeast. The linker of the nucleoskeleton and cytoskeleton (LINC) complex is
Jinbo Fan +3 more
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Diverse plasma membrane protrusions act as platforms for extracellular vesicle shedding
Journal of Extracellular Vesicles, 2021 Plasma membrane curvature is an important factor in the regulation of cellular phenotype and is critical for various cellular activities including the shedding of extracellular vesicles (EV).
Kirsi Rilla
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MG53 Regulates Membrane Budding and Exocytosis in Muscle Cells [PDF]
Journal of Biological Chemistry, 2009 Membrane recycling and remodeling contribute to multiple cellular functions, including cell fusion events during myogenesis. We have identified a tripartite motif (TRIM72) family member protein named MG53 and defined its role in mediating the dynamic process of membrane fusion and exocytosis in striated muscle.
Chuanxi, Cai +7 more
openaire +2 more sources
Advanced Science, EarlyView.Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Packaging of actin into Ebola virus VLPs
Virology Journal, 2005 The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses.
Harty Ronald N, Han Ziying
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Domain-induced budding of fluid membranes
Biophysical Journal, 1993 Domains within fluid membranes grow by the aggregation of molecules which diffuse laterally within the membrane matrix. A simple theoretical model is introduced which predicts that a flat or weakly curved domain becomes unstable at a certain limiting size and then undergoes a budding or invagination process.
openaire +3 more sources
The rim15-Endosulfine-PP2ACdc55 signalling module regulates entry into gametogenesis and quiescence via distinct mechanisms in budding yeast [PDF]
, 2013 Quiescence and gametogenesis represent two distinct survival strategies in response to nutrient starvation in budding yeast. Precisely how environmental signals are sensed by yeast cells to trigger quiescence and gametogenesis is not fully understood.
Sourav Sarkar +21 more
core +1 more source