Results 31 to 40 of about 1,114,517 (249)

Quantitative Live-Cell Imaging of Human Immunodeficiency Virus (HIV-1) Assembly [PDF]

open access: yes, 2012
Advances in fluorescence methodologies make it possible to investigate biological systems in unprecedented detail. Over the last few years, quantitative live-cell imaging has increasingly been used to study the dynamic interactions of viruses with cells ...
Barbara Müller   +5 more
core   +1 more source

Roles of the three L-domains in β-retrovirus budding [PDF]

open access: yes, 2015
Retroviral Gag protein plays a critical role during the late stage of virus budding and possesses a so-called L-domain containing PT/SAP, PPxY, YxxL or FPIV motifs that are critical for efficient budding.
Jiro Yasuda   +4 more
core   +1 more source

The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism.

open access: yesPLoS Pathogens, 2022
During replication, herpesviral capsids are translocated from the nucleus into the cytoplasm by an unusual mechanism, termed nuclear egress, that involves capsid budding at the inner nuclear membrane.
Michael K Thorsen   +2 more
doaj   +1 more source

Diffuso-kinetic membrane budding dynamics

open access: yesSoft Matter, 2020
A wide range of proteins create shape transformations of membranes. The remodeling is a coupling between the energetic cost of membrane bending, protein recruitment which induce local spontaneous curvature and protein diffusion on the membrane.
Rossana Rojas Molina   +4 more
openaire   +4 more sources

The road not taken: Less traveled roads from the TGN to the plasma membrane [PDF]

open access: yes, 2015
: The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane. Over the years, it has become clear that more than one transport pathway promotes plasma
Anne Spang, Spang, Anne
core   +1 more source

Association of Influenza Virus Proteins with Membrane Rafts

open access: yesAdvances in Virology, 2011
Assembly and budding of influenza virus proceeds in the viral budozone, a domain in the plasma membrane with characteristics of cholesterol/sphingolipid-rich membrane rafts.
Michael Veit, Bastian Thaa
doaj   +1 more source

Virus Entry, Assembly, Budding, and Membrane Rafts [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2003
SUMMARY As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries for completion of their replication cycle. The recent discovery of the heterogeneous distribution of the various lipids within cell membranes has led to the proposal that sphingolipids and cholesterol tend to segregate in ...
Nathalie, Chazal, Denis, Gerlier
openaire   +2 more sources

Dynamics of Nonequilibrium Membrane Bud Formation [PDF]

open access: yesPhysical Review Letters, 2004
The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or membrane curvature, depending upon the spatial extent of the perturbation.
openaire   +4 more sources

Bending a membrane: How clathrin affects budding [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Receptor-mediated endocytosis of ligands, such as transferrin and LDL, is suppressed when clathrin synthesis is blocked by RNA interference in HeLa cells. We have found that domains containing the adapter complex 2 (AP2)-coated vesicle adapter and the endocytic accessory proteins CALM (clathrin assembly lymphoid myeloid leukemia protein), epsin, and ...
Lars, Hinrichsen   +3 more
openaire   +2 more sources

The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding. [PDF]

open access: yesPLoS Pathogens, 2016
HIV virions assemble on the plasma membrane and bud out of infected cells using interactions with endosomal sorting complexes required for transport (ESCRTs). HIV protease activation is essential for maturation and infectivity of progeny virions, however,
Mourad Bendjennat, Saveez Saffarian
doaj   +1 more source

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