Alterations of membrane curvature during influenza virus budding [PDF]
Biochemical Society Transactions, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
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Budding and vesiculation induced by conical membrane inclusions [PDF]
Physical Review E, 2009 Conical inclusions in a lipid bilayer generate an overall spontaneous curvature of the membrane that depends on concentration and geometry of the inclusions. Examples are integral and attached membrane proteins, viruses, and lipid domains.
B. Alberts +5 more
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Tilt Texture Domains on a Membrane and Chirality induced Budding [PDF]
Physical Review Letters, 2001 We study the equilibrium conformations of a lipid domain on a planar fluid membrane where the domain is decorated by a vector field representing the tilt of the stiff fatty acid chains of the lipid molecules, while the surrounding membrane is fluid and ...
A. Radhakrishnan +20 more
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Programmable DNA shell scaffolds for directional membrane budding [PDF]
Nature CommunicationsIn the pursuit of replicating biological processes at the nanoscale, controlling cellular membrane dynamics has emerged as a key area of interest. Here, we report a system mimicking virus assembly to control directional membrane budding.
Michael T. Pinner, Hendrik Dietz
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Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs [PDF]
Cell Reports, 2016 DYT1 dystonia is a neurodevelopmental disease that manifests during a discrete period of childhood. The disease is caused by impaired function of torsinA, a protein linked to nuclear membrane budding.
Lauren M. Tanabe +2 more
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Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response [PDF]
Advanced ScienceRadiotherapy failure often arises from tumor repopulation by treatment‐resistant cancer cells. Following irradiation, cancer cells can undergo endoreplication to form polyploid giant cancer cells (PGCCs)—radiation‐persistent cells capable of generating ...
Zheng Deng +20 more
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Membrane transformations of fusion and budding
Nature CommunicationsMembrane fusion and budding mediate fundamental processes like intracellular trafficking, exocytosis, and endocytosis. Fusion is thought to open a nanometer-range pore that may subsequently close or dilate irreversibly, whereas budding transforms flat ...
Ling-Gang Wu, Chung Yu Chan
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Bud-neck scaffolding as a possible driving force in ESCRT-induced membrane budding. [PDF]
Biophys J, 2015 Membrane budding is essential for processes such as protein sorting and transport. Recent experimental results with ESCRT proteins reveal a novel budding mechanism, with proteins emerging in bud necks but separated from the entire bud surface.
Mercker M, Marciniak-Czochra A.
europepmc +4 more sources
The Mechanism of Budding of Retroviruses from Cell Membranes [PDF]
Advances in Virology, 2009 Retroviruses have evolved a mechanism for the release of particles from the cell membrane that appropriates cellular protein complexes, referred to as ESCRT-I, -II, -III, normally involved in the biogenesis of multivesicular bodies.
Andrew Pincetic, Jonathan Leis
doaj +3 more sources
Clathrin mediates membrane fission and budding by constricting membrane pores
Cell DiscoveryMembrane budding, which underlies fundamental processes like endocytosis, intracellular trafficking, and viral infection, is thought to involve membrane coat-forming proteins, including the most observed clathrin, to form Ω-shape profiles and helix ...
Lisi Wei +23 more
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