Results 1 to 10 of about 1,114,517 (249)

The Energy of COPI for Budding Membranes. [PDF]

open access: yesPLoS ONE, 2015
As a major actor of cellular trafficking, COPI coat proteins assemble on membranes and locally bend them to bud 60 nm-size coated particles. Budding requires the energy of the coat assembly to overcome the one necessary to deform the membrane which ...
Abdou Rachid Thiam, Frédéric Pincet
doaj   +4 more sources

Elasticity‐Driven Membrane Budding through Cholesterol Concentration on Supported Lipid Monolayer–Bilayer Junction

open access: yesAdvanced Materials Interfaces, 2020
Membrane budding is an essential process during various biological activities, such as intercellular communication and transportation of life‐sustaining molecules and signals, which primarily occur with the aid of particular proteins.
Yeon Kyung Lee   +3 more
doaj   +2 more sources

Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering

open access: yesmBio, 2021
During replication of herpesviruses, capsids escape from the nucleus into the cytoplasm by budding at the inner nuclear membrane. This unusual process is mediated by the viral nuclear egress complex (NEC) that deforms the membrane around the capsid by ...
Michael K. Thorsen   +6 more
doaj   +3 more sources

Budding and Fission of Membrane Vesicles: A Mini Review

open access: yesFrontiers in Physics, 2020
In this mini-review, a brief historical survey of the mechanisms which determine the shapes of liposomes and cells and the budding and fission of their membrane is presented.
Samo Penič   +9 more
doaj   +3 more sources

Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes. [PDF]

open access: yesPLoS Computational Biology, 2012
The formation of vesicles is essential for many biological processes, in particular for the trafficking of membrane proteins within cells. The Endosomal Sorting Complex Required for Transport (ESCRT) directs membrane budding away from the cytosol. Unlike
Bartosz Różycki   +3 more
doaj   +1 more source

Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress. [PDF]

open access: yesPLoS Pathogens, 2015
Herpesviruses acquire their envelope by budding into the lumen of cytoplasmic membrane vesicles. This process is initiated by component(s) on viral particles, which recognize the budding site where the viral glycoproteins are present and recruit cellular
Xin Wang   +5 more
doaj   +1 more source

Femtoliter Injection of ESCRT-III Proteins into Adhered Giant Unilamellar Vesicles

open access: yesBio-Protocol, 2022
The endosomal sorting complex required for transport (ESCRT) machinery mediates membrane fission reactions that exhibit a different topology from that observed in clathrin-coated vesicles.
Vasil Georgiev   +3 more
doaj   +1 more source

Structural Basis for Capsid Recruitment and Coat Formation during HSV-1 Nuclear Egress

open access: yesProceedings, 2020
During herpesvirus infection, nascent viral capsids egress the nucleus into the cytoplasm by an unusual mechanism whereby capsids bud at the inner nuclear membrane.
Elizabeth Draganova   +3 more
doaj   +3 more sources

A large extension to HIV-1 Gag, like Pol, has negative impacts on virion assembly. [PDF]

open access: yesPLoS ONE, 2012
The GagPol protein of HIV-1 harbors viral enzymes, such as protease (PR), reverse transcriptase, and integrase, that are all crucial for virion infectivity.
Hiyori Haraguchi   +3 more
doaj   +1 more source

Electron tomography reveals the steps in filovirus budding. [PDF]

open access: yesPLoS Pathogens, 2010
The filoviruses, Marburg and Ebola, are non-segmented negative-strand RNA viruses causing severe hemorrhagic fever with high mortality rates in humans and nonhuman primates.
Sonja Welsch   +5 more
doaj   +1 more source

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