Membrane Curvature: The Inseparable Companion of Autophagy [PDF]
Cells, 2023 Autophagy is a highly conserved recycling process of eukaryotic cells that degrades protein aggregates or damaged organelles with the participation of autophagy-related proteins.
Lei Liu +12 more
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Phospholipases and Membrane Curvature: What Is Happening at the Surface? [PDF]
Membranes, 2023 In this revision work, we emphasize the close relationship between the action of phospholipases and the modulation of membrane curvature and curvature stress resulting from this activity.
María Laura Fanani +1 more
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Membrane curvature initiates Cdc42-FBP17-N-WASP clustering and actin nucleation [PDF]
The EMBO JournalThe architecture of actin networks at the cell surface is regulated by local membrane topology. However, how actin nucleation can respond sensitively to the degree of membrane curvature remains incompletely understood.
Kexin Zhu +6 more
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Out-of-equilibrium mechanochemistry and self-organization of fluid membranes interacting with curved proteins [PDF]
New Journal of Physics, 2019 The function of biological membranes is controlled by the interaction of the fluid lipid bilayer with various proteins, some of which induce or react to curvature.
Caterina Tozzi +2 more
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Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments [PDF]
Biomolecules, 2023 The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment.
Peng Xie +5 more
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Exploration and analytical techniques for membrane curvature-sensing proteins in bacteria [PDF]
Journal of BacteriologyThe mechanism by which cells regulate protein localization is an important topic in the field of bacterial biology. In certain instances, the morphology of the biological membrane has been demonstrated to function as a spatial cue for the subcellular ...
Takumi Komikawa +2 more
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Membrane curvature sensing and symmetry breaking of the M2 proton channel from Influenza A [PDF]
eLifeThe M2 proton channel aids in the exit of mature influenza viral particles from the host plasma membrane through its ability to stabilize regions of high negative Gaussian curvature (NGC) that occur at the neck of budding virions.
James Lincoff +4 more
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Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View [PDF]
Cells, 2022 In addition to its structural role in enclosing and protecting the genome, the nuclear envelope (NE) forms a highly adaptive communication interface between the cytoplasm and the nuclear interior in eukaryotic cells.
Bas W. A. Peeters +2 more
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The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature [PDF]
The EMBO JournalThe C2-WW-HECT domain ubiquitin ligase Nedd4L regulates membrane sorting during endocytosis through the ubiquitination of cargo molecules such as the epithelial sodium channel (ENaC). Nedd4L is catalytically autoinhibited by an intramolecular interaction
Yasuhisa Sakamoto +7 more
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TGFβ-induced changes in membrane curvature influence Ras oncoprotein membrane localization [PDF]
Scientific Reports, 2022 In the course of cancer progression tumor cells undergo morphological changes that lead to increased motility and invasiveness thus promoting formation of metastases.
Alexandros Damalas +3 more
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