Results 51 to 60 of about 165,610 (282)

Reliable estimation of membrane curvature for cryo-electron tomography.

PLoS Computational Biology, 2020
Curvature is a fundamental morphological descriptor of cellular membranes. Cryo-electron tomography (cryo-ET) is particularly well-suited to visualize and analyze membrane morphology in a close-to-native state and molecular resolution.
Maria Salfer, Javier F Collado, Wolfgang Baumeister, Rubén Fernández-Busnadiego, Antonio Martínez-Sánchez   +4 more
doaj   +1 more source

Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release

eLife, 2020
Vesicle fusion is mediated by assembly of SNARE proteins between opposing membranes. While previous work suggested an active role of SNARE transmembrane domains (TMDs) in promoting membrane merger (Dhara et al., 2016), the underlying mechanism remained ...
Madhurima Dhara, Maria Mantero Martinez, Mazen Makke, Yvonne Schwarz, Ralf Mohrmann, Dieter Bruns   +5 more
doaj   +1 more source

Continuum Electromechanical Modeling of Protein-Membrane Interaction

, 2010
A continuum electromechanical model is proposed to describe the membrane curvature induced by electrostatic interactions in a solvated protein-membrane system.
Alemayehu A. Gorfe, Benzhuo Lu, N. Kikuchi, P. G. Ciarlet, Y. C. Zhou   +4 more
core   +1 more source

Curvature-Mediated Interactions Between Membrane Proteins [PDF]

Biophysical Journal, 1998
Membrane proteins can deform the lipid bilayer in which they are embedded. If the bilayer is treated as an elastic medium, then these deformations will generate elastic interactions between the proteins. The interaction between a single pair is repulsive.
Kim, K.S., Neu, John, Oster, George
openaire   +2 more sources

Interplay of membrane crosslinking and curvature induction by annexins

Scientific Reports, 2022
Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanistic studies of
Anna Mularski, Stine Lauritzen Sønder, Anne Sofie Busk Heitmann, Mayank Prakash Pandey, Himanshu Khandelia, Jesper Nylandsted, Adam Cohen Simonsen   +6 more
doaj   +1 more source

The one-loop elastic coefficients for the Helfrich membrane in higher dimensions

, 2005
Using a covariant geometric approach we obtain the effective bending couplings for a 2-dimensional rigid membrane embedded into a $(2+D)$-dimensional Euclidean space.
A Zamora, Birrel N D, Canham P, Capovilla R, Capovilla R, Capovilla R, Capovilla R Guven J Santiago J A, Chaikin P M, DeWitt B S, Helfrich W, Helfrich W, J A Santiago, Kleinert H, Kleinert H, Lipowsky R, Nelson D, Nishiyama Y, Peliti L F David P Ginsparg J Zinn-Justin, Pinnow H A, Polchinski J, Polyakov A M, Safran S, Vilenkin A   +22 more
core   +1 more source

Recursive Alterations of the Relationship between Simple Membrane Geometry and Insertion of Amphiphilic Motifs

Membranes, 2017
The shape and composition of a membrane directly regulate the localization, activity, and signaling properties of membrane associated proteins. Proteins that both sense and generate membrane curvature, e.g., through amphiphilic insertion motifs ...
Kenneth Lindegaard Madsen, Rasmus Herlo
doaj   +1 more source

Interdisciplinary Synergy to Reveal Mechanisms of Annexin-Mediated Plasma Membrane Shaping and Repair

Cells, 2020
The plasma membrane surrounds every single cell and essentially shapes cell life by separating the interior from the external environment. Thus, maintenance of cell membrane integrity is essential to prevent death caused by disruption of the plasma ...
Poul Martin Bendix, Adam Cohen Simonsen, Christoffer D. Florentsen, Swantje Christin Häger, Anna Mularski, Ali Asghar Hakami Zanjani, Guillermo Moreno-Pescador, Martin Berg Klenow, Stine Lauritzen Sønder, Helena M. Danielsen, Mohammad Reza Arastoo, Anne Sofie Heitmann, Mayank Prakash Pandey, Frederik Wendelboe Lund, Catarina Dias, Himanshu Khandelia, Jesper Nylandsted   +16 more
doaj   +1 more source

Membrane Localization of Piezo1 in the Context of Its Role in the Regulation of Red Blood Cell Volume

Frontiers in Physiology, 2022
Piezo1 is a membrane nonspecific cation channel involved in red blood cells (RBCs) in the regulation of their volume. Recently, it was shown that it is distributed on the RBC membrane in a nonuniform manner.
Bojan Božič, Saša Svetina, Saša Svetina   +2 more
doaj   +1 more source

Septins recognize micron-scale membrane curvature [PDF]

Journal of Cell Biology, 2016
How cells recognize membrane curvature is not fully understood. In this issue, Bridges et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512029) discover that septins, a component of the cytoskeleton, recognize membrane curvature at the micron scale, a common morphological hallmark of eukaryotic cellular processes.
Lobato-Márquez, D, Mostowy, S
openaire   +4 more sources