Results 11 to 20 of about 854,659 (323)

The Effects of Regulatory Lipids on Intracellular Membrane Fusion Mediated by Dynamin-Like GTPases

open access: yesFrontiers in Cell and Developmental Biology, 2020
Membrane fusion mediates a number of fundamental biological processes such as intracellular membrane trafficking, fertilization, and viral infection. Biological membranes are composed of lipids and proteins; while lipids generally play a structural role,
Yeojin Moon, Youngsoo Jun
doaj   +1 more source

A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization

open access: yesBiomolecules, 2023
Viral entry and fertilization are distinct biological processes that share a common mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell membrane, triggering a series of conformational changes in the viral fusion proteins.
Farshad C. Azimi   +5 more
doaj   +1 more source

Membrane fusion

open access: yesCurrent Opinion in Cell Biology, 2002
Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins.
Jahn, R., Grubmueller, H.
openaire   +6 more sources

New Biophysical Approaches Reveal the Dynamics and Mechanics of Type I Viral Fusion Machinery and Their Interplay with Membranes

open access: yesViruses, 2020
Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
doaj   +1 more source

Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection. [PDF]

open access: yesPLoS ONE, 2013
Chlamydia trachomatis replicates in a parasitophorous membrane-bound compartment called an inclusion. The inclusions corrupt host vesicle trafficking networks to avoid the degradative endolysosomal pathway but promote fusion with each other in order to ...
Erik Ronzone, Fabienne Paumet
doaj   +1 more source

Phospholipases and Membrane Curvature: What Is Happening at the Surface?

open access: yesMembranes, 2023
In this revision work, we emphasize the close relationship between the action of phospholipases and the modulation of membrane curvature and curvature stress resulting from this activity.
María Laura Fanani   +1 more
doaj   +1 more source

A supramolecular system mimicking the infection process of an enveloped virus through membrane fusion

open access: yesScientific Reports, 2023
Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa   +3 more
doaj   +1 more source

Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore

open access: yesFrontiers in Cell and Developmental Biology, 2021
SNARE-dependent membrane fusion is essential for neurotransmitter release at the synapse. Recently, α-synuclein has emerged as an important regulator for membrane fusion. Misfolded α-synuclein oligomers are potent fusion inhibitors. However, the function
Ryan Khounlo   +6 more
doaj   +1 more source

TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

open access: yesCell Reports, 2021
Summary: Neuronal morphogenesis involves dramatic plasma membrane expansion, fueled by soluble N-ethylmaleimide-sensitive factor attachment protein eceptors (SNARE)-mediated exocytosis.
Fabio L. Urbina   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy