Results 11 to 20 of about 854,659 (323)
The Effects of Regulatory Lipids on Intracellular Membrane Fusion Mediated by Dynamin-Like GTPases
Membrane fusion mediates a number of fundamental biological processes such as intracellular membrane trafficking, fertilization, and viral infection. Biological membranes are composed of lipids and proteins; while lipids generally play a structural role,
Yeojin Moon, Youngsoo Jun
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A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization
Viral entry and fertilization are distinct biological processes that share a common mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell membrane, triggering a series of conformational changes in the viral fusion proteins.
Farshad C. Azimi +5 more
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Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins.
Jahn, R., Grubmueller, H.
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Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
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Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection. [PDF]
Chlamydia trachomatis replicates in a parasitophorous membrane-bound compartment called an inclusion. The inclusions corrupt host vesicle trafficking networks to avoid the degradative endolysosomal pathway but promote fusion with each other in order to ...
Erik Ronzone, Fabienne Paumet
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Phospholipases and Membrane Curvature: What Is Happening at the Surface?
In this revision work, we emphasize the close relationship between the action of phospholipases and the modulation of membrane curvature and curvature stress resulting from this activity.
María Laura Fanani +1 more
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The ARF regulatory GTPase in Giardia intestinalis is associated with vesicle formation and membrane fusion machinery at non-canonical endosomal compartments [PDF]
Pipaliya SV +6 more
europepmc +2 more sources
Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa +3 more
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Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore
SNARE-dependent membrane fusion is essential for neurotransmitter release at the synapse. Recently, α-synuclein has emerged as an important regulator for membrane fusion. Misfolded α-synuclein oligomers are potent fusion inhibitors. However, the function
Ryan Khounlo +6 more
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TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47
Summary: Neuronal morphogenesis involves dramatic plasma membrane expansion, fueled by soluble N-ethylmaleimide-sensitive factor attachment protein eceptors (SNARE)-mediated exocytosis.
Fabio L. Urbina +6 more
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