Results 191 to 200 of about 126,108 (313)

Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody [PDF]

, 1980
Rodger P. McEver, Nancy Lewis Baenziger, Philip W. Majerus   +2 more
openalex   +1 more source

MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery

Advanced Science, EarlyView.
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li, Youhan Sun, Xinyu Qin, Xin Gao, Guohua Wang   +4 more
wiley   +1 more source

Altered glycosylation of EVs in cancers: galectin-3-binding protein (LGALS3BP). [PDF]

Discov Oncol
Koh Kok JY, Goh BH, Lee WL.
europepmc   +1 more source

Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions. [PDF]

J Proteome Res, 2015
Allam H, Aoki K, Benigno BB, McDonald JF, Mackintosh SG, Tiemeyer M, Abbott KL.   +6 more
europepmc   +1 more source

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

Integrative glycomic analysis reveals the crucial role of protein glycosylation in fungal pathogenesis. [PDF]

PLoS Pathog
Moon H, Thak EJ, Choi Y, Kim S, Park J, Lee N, Shin S, Jeon H, Winarto J, Choi S, Shin JY, Kim JE, Song DG, Kim H, Choi GJ, Kang HA, Son H.   +16 more
europepmc   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

Advanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li, Jiajun Tan, Chuqing Zhou, Siyi Zhou, Yuanli Ye, Xinzhu Li, Xinyu Shen, Tian Xie, Mengyue Wang, Jingwei Jiang, Yiping Zhao, Xiao Xiang, Yong Zhou, Jun Wu, Cheng‐Ming Chuong, Mingxing Lei   +15 more
wiley   +1 more source

Deciphering the Metabolic Impact and Clinical Relevance of N-Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling. [PDF]

Adv Sci (Weinh)
Liu G, Chen L, Zhao J, Jiang Y, Guo Y, Mao X, Ren X, Liu K, Mei Q, Li Q, Huang H.   +10 more
europepmc   +1 more source

Formation of the Semliki Forest Virus Membrane Glycoprotein Complexes in the Infected Cell

, 1980
Andrew Ziemiecki, Henrik Garoff, Kai Simons   +2 more
openalex   +1 more source

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

Advanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang, Ting Sun, Si‐tu Xue, Zhong‐di Cai, Hong Yi, Miao Lv, Shi‐bo Kou, Rui Liu, Xiao‐zhong Peng, Zhuo‐rong Li   +9 more
wiley   +1 more source