Results 101 to 110 of about 678,998 (299)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Digital Holographic Microscopy of Phase Separation in Multicomponent Lipid Membranes [PDF]

open access: yes, 2016
Lateral in-homogeneities in lipid compositions cause microdomains formation and change in the physical properties of biological membranes. With the presence of cholesterol and mixed species of lipids, phospholipid membranes segregate into lateral domains
Darudi, Ahmad   +3 more
core   +1 more source

Inclusions induced phase separation in mixed lipid film

open access: yes, 1999
The effect of rigid inclusions on the phase behavior of a film containing a mixture of lipid molecules is investigated. In the proposed model, the inclusion-induced deformation of the film, and the resulting energy cost are strongly dependent upon the ...
Safran, S., Sens, P.
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Domain formation in membranes with quenched protein obstacles: Lateral heterogeneity and the connection to universality classes

open access: yes, 2010
We show that lateral fluidity in membranes containing quenched protein obstacles belongs to the universality class of the two-dimensional random-field Ising model.
Fischer, T., Vink, R. L. C.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

PROSPECTS OF DOMESTIC MICRO-INGREDIENTS PRODUCTION [PDF]

open access: yesТехника и технология пищевых производств, 2016
Due to the continuous increase in the volume of different types of food additives application for technological purposes, a deep studying of approaches and decisions on the production and development of raw sources of reproduction is urgent and demanded.
Starovoytova K.V., Terechuk L.V.
doaj  

Permeability across lipid membranes

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2016
Molecular permeation through lipid membranes is a fundamental biological process that is important for small neutral molecules and drug molecules. Precise characterization of free energy surface and diffusion coefficients along the permeation pathway is required in order to predict molecular permeability and elucidate the molecular mechanisms of ...
openaire   +2 more sources

Painted supported lipid membranes

open access: yesBiophysical Journal, 1993
We report herein measurements on a novel type of supported lipid films, which we call painted supported membranes (PSM). These membranes are formed in a self-assembly process on alkylated gold films from an organic solution. The formation process was investigated with surface plasmon resonance microscopy.
Florin, E.-L., Gaub, H.E.
openaire   +2 more sources

Effects of Growth Temperatures on the Fatty Acid Composition of Isolated Chloroplasts From Two Species Differing in Heat Sensitivity [PDF]

open access: yes, 1985
Lipid analyses of chloroplasts isolated from wheat (Triticum aestivum L. cv. Arthur) and milo (Sorghum bicolor cv. Funk\u27s hybrid 522) suggest no major heat effect on lipid class distribution.
Gehring, Roy Z., Todd, Glenn W.
core   +2 more sources

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