Results 121 to 130 of about 433,130 (308)
Influence of lipids on protein-mediated transmembrane transport [PDF]
, 2013 : Transmembrane proteins are responsible for transporting ions and small molecules across the hydrophobic region of the cell membrane. We are reviewing the evidence for regulation of these transport processes by interactions with the lipids of the ...
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Editorial: Membrane lipids in T cell functions [PDF]
, 2018 Plasma membrane lipids play essential roles in regulating T cell signaling, differentiation, and effector functions. The major lipid species in the plasma membrane are glycerophospholipids, sphingolipids, and sterol lipids.
Tuosto, Loretta, Xu, Chenqi
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Redox BiologyAdolescent depression is a globally concerned mental health issue, the pathophysiological mechanisms of which remain elusive. Membrane lipids play a crucial role in brain development and function, potentially serving as a crossroad for the abnormalities ...
Jinfeng Wang +9 more
doaj +1 more source
Grasas y Aceites, 1998 We studied the effect of virgin olive oil on plasma lipids and erythrocyte membrane lipids of healthy subjects and hypertensive patients (with or without hypercholesterolaemia). The effect of high-oleic sunflower oil was also tested.
V. Ruiz Gutiérrez +2 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Computational nanoscience and molecular modelling of shock wave interactions with biological membranes [PDF]
, 2011 Lateral diffusion of membrane components (lipids and proteins) is an important membrane property to measure since the essential process of absorption of anti-cancer and other drugs -some of which are not soluble in lipids and therefore would not be ...
Sourmaidou, Damiani
core
Mobile and Immobile Obstacles in Supported Lipid Bilayer Systems and Their Effect on Lipid Mobility
Colloids and InterfacesDiffusion and immobilization of molecules in biomembranes are essential for life. Understanding it is crucial for biomimetic approaches where well-defined substrates are created for live cell assays or biomaterial development. Here, we present biomimetic
Luisa Coen +3 more
doaj +1 more source
Low-intensity light stress on broccoli seedlings: associated mechanisms of acclamatory stress tolerance through changes in pigments, membrane lipids, and amelioration of antioxidative defense systems [PDF]
Brazilian Journal of BiologyLow-intensity light (LL; 100 µmol m–2 s–1PPFD) effects on growth and biochemical parameters indicative of acclimation were investigated on 21-day-old broccoli seedlings. LL stress reduces the biomass and thickness of the leaf.
G. Alpamyssova +6 more
doaj +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source