Results 81 to 90 of about 1,682,039 (300)
Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids
, 2021 Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint for the entry and passage of signals and other molecules. Their composition can be modulated by diet, pathophysiological processes, and nutritional/pharmaceutical ...
Ramón Román +9 more
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Molecules, 2012 In this paper a rapid and highly efficient method for controlled incorporation of fluorescent lipids into living mammalian cells is introduced. Here, the fluorescent molecules have two consecutive functions: First, they trigger rapid membrane fusion ...
Christian Kleusch +4 more
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Functionalized Membrane Domains: An Ancestral Feature of Archaea?
Frontiers in Microbiology, 2020 Bacteria and Eukarya organize their plasma membrane spatially into domains of distinct functions. Due to the uniqueness of their lipids, membrane functionalization in Archaea remains a debated area. A novel membrane ultrastructure predicts that monolayer
Maxime Tourte +3 more
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Lipids in membrane protein structures
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2004 This review describes the recent knowledge about tightly bound lipids in membrane protein structures and deduces general principles of the binding interactions. Bound lipids are grouped in annular, nonannular, and integral protein lipids. The importance of lipid binding for vertical positioning and tight integration of proteins in the membrane, for ...
Palsdottir, Hildur, Hunte, Carola
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The effect of modulating membrane lipid composition on the thermal sensitivity of tumour cells in culture [PDF]
, 1989 The plasma membrane, which separates intracellular contents from extra cellular milieu, consists of a lipid bilayer comprising mainly phospholipids and cholesterol together with various functional proteins, which control the interaction of the cell with ...
Kingston, Catharine Alison
core
Journal of Structural Biology: XPhysical properties of biological membranes directly or indirectly govern biological processes. Yet, the interplay between membrane and integral membrane proteins is difficult to assess due to reciprocal effects between membrane proteins, individual ...
Evan J. van Aalst +5 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Mechanisms regulating the acyl chain composition of membrane lipids in S. cerevisiae [PDF]
, 2011 The goal of the research described in this thesis was to identify the genes/enzymes involved in acyl chain remodeling of the major membrane lipid phosphatidylcholine (PC) in the model eukaryote S. cerevisiae. A database search yielded 75 candidates with (
De Smet, C.H. +3 more
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Electrodiffusion of lipids on membrane surfaces [PDF]
The Journal of Chemical Physics, 2012 Lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when the random lateral motion is mediated by the electrostatic interactions and membrane curvature.
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