Results 41 to 50 of about 3,142,426 (357)
Trends in Cell Biology, 1998 The thin membrane of the endoplasmic reticulum matures into the thick plasma membrane in the Golgi apparatus. Along the way, the concentrations of cholesterol and sphingolipids increase. Here, Gerrit van Meer discusses how this phenomenon may reflect an intricate lipid-protein sorting machinery.
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Membrane curvature sorts lipids [PDF]
EMBO reports, 2005 The enrichment of sphingolipids and cholesterol in the mammalian plasma membrane, and unsaturated phosphatidylcholine (PC) in the endoplasmic reticulum, requires lipid sorting in the Golgi apparatus. Most sphingolipids are synthesized in the Golgi lumen (Holthuis & Levine, 2005).
van Meer, G., Vaz, W.L.C.
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PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids
Journal of Lipid Research, 2020 The plasma membrane of neurons consists of distinct domains, each of which carries specialized functions and a characteristic set of membrane proteins.
Hideaki Kuge +3 more
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Sensors, 2022 There is extensive interest in developing real-time biosensing strategies to characterize the membrane-disruptive properties of antimicrobial lipids and surfactants.
Sue Woon Tan +3 more
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Monolayer spontaneous curvature of raft-forming membrane lipids [PDF]
Soft Matter, 2013 Monolayer spontaneous curvatures for cholesterol, DOPE, POPE, DOPC, DPPC, DSPC, POPC, SOPC, and egg sphingomyelin were obtained using small-angle X-ray scattering (SAXS) on inverted hexagonal phases (HII). Spontaneous curvatures of bilayer forming lipids
B. Kollmitzer +3 more
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Nature Materials, 2021 Endosomal escape remains a fundamental barrier hindering the advancement of nucleic acid therapeutics. Taking inspiration from natural phospholipids that comprise biological membranes, we report the combinatorial synthesis of multi-tailed ionizable ...
Shuai Liu +6 more
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Tear of lipid membranes by nanoparticles
Soft Matter, 2022 Tear, a direct physical damage of lipid bilayers, can be inflicted by small enough nanoparticles.
Er-Rafik, Meriem +7 more
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Frontiers in Microbiology, 2021 Flavivirus replication occurs in membranous replication compartments, also known as replication organelles (ROs) derived from the host ER membrane. Our previous study showed that the non-structural (NS) protein 1 (NS1) is the essential factor for RO ...
Yali Ci +8 more
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Lipid21: Complex Lipid Membrane Simulations with AMBER
Journal of Chemical Theory and Computation, 2022 We extend the modular AMBER lipid force field to include anionic lipids, polyunsaturated fatty acid (PUFA) lipids, and sphingomyelin, allowing the simulation of realistic cell membrane lipid compositions, including raft-like domains.
Callum J. Dickson, R. Walker, I. Gould
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source