Results 71 to 80 of about 2,473,220 (258)

Membrane biology: Do glycolipid microdomains really exist? [PDF]

Current Biology, 1998
Glycolipid membrane domains have been suggested to have a number of physiological functions, but do they actually exist in vivo or are they artefacts of extraction procedures? Recent data go some way towards showing that such glycolipid domains really are present within both model and cellular membranes.
openaire   +2 more sources

Plasma membrane microdomains: Organization, function and trafficking (Review) [PDF]

Molecular Membrane Biology, 2004
The plasma membrane consists of a mosaic of functional microdomains facilitating a variety of physiological processes associated with the cell surface. In most cells, the majority of the cell surface is morphologically featureless, leading to difficulties in characterizing its organization and microdomain composition.
Laude AJ, Prior IA
openaire   +3 more sources

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

The stomatin-like protein StlP organizes membrane microdomains to govern polar growth in filamentous actinobacteria under hyperosmotic stress

Nature Communications
The cell wall represents an essential structure conserved among most bacteria, playing a crucial role in growth and development. While extensively studied model bacteria have provided insights into cell wall synthesis coordination, the mechanism ...
Xiaobo Zhong, Sarah S. M. Baur, Veronique M. A. Ongenae, Guillermo Guerrero Egido, Shraddha Shitut, Chao Du, Erik Vijgenboom, Gilles P. van Wezel, Victor Carrion Bravo, Ariane Briegel, Marc Bramkamp, Dennis Claessen   +11 more
doaj   +1 more source

Pathogenic podocin variants exhibit distinct defects in trafficking, membrane organization, and degradation pathways

European Journal of Cell Biology
Nephrotic syndrome is frequently associated with pathogenic variants in NPHS2 (podocin), including the common and severe R138Q substitution. Using conditionally immortalized human podocytes expressing Myc-tagged podocin variants (G92C, V180M, R138Q ...
Pei-Chen Lu, Ruth Rollason, Chia-An Chou, Valeryia Kuzmuk, Kate J. Heesom, Moin A. Saleem, Gavin I. Welsh   +6 more
doaj   +1 more source

Calcium Microdomain Formation at the Perisynaptic Cradle Due to NCX Reversal: A Computational Study

Frontiers in Cellular Neuroscience, 2019
It has recently been proposed using a multi-compartmental mathematical model that negatively fixed charged membrane-associated sites constrain the flow of cations in perisynaptic astroglial processes.
John Joseph Wade, Kevin Breslin, KongFatt Wong-Lin, Jim Harkin, Bronac Flanagan, Harm Van Zalinge, Steve Hall, Mark Dallas, Angela Bithell, Alexei Verkhratsky, Alexei Verkhratsky, Liam McDaid   +11 more
doaj   +1 more source

Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points.

PLoS Genetics, 2022
After endocytosis, transmembrane cargo is differentially sorted into degradative or recycling pathways. This process is facilitated by recruitment into physically distinct degradative or recycling microdomains on the limiting membrane of individual ...
Anne Norris, Collin T McManus, Simon Wang, Ruochen Ying, Barth D Grant   +4 more
doaj   +1 more source

Emergent Freestanding Complex Oxide Membranes for Multifunctional Applications

Advanced Materials, EarlyView.
This review surveys freestanding oxide membranes and covers fabrication and three pathways for studies and devices: strain‐free and strained membranes, and van der Waals‐integrated heterostructures. We show how coupled oxide responses map onto these routes and cross‐couple to expand behaviors.
Baowen Li, Yanran Liu, Jinjin Liu, Josephine Si Yu See, Kaijian Xing, Dong‐Chen Qi, Xiao Renshaw Wang   +6 more
wiley   +1 more source

Potassium and sodium microdomains in thin astroglial processes: A computational model study. [PDF]

PLoS Computational Biology, 2018
A biophysical model that captures molecular homeostatic control of ions at the perisynaptic cradle (PsC) is of fundamental importance for understanding the interplay between astroglial and neuronal compartments.
Kevin Breslin, John Joseph Wade, KongFatt Wong-Lin, Jim Harkin, Bronac Flanagan, Harm Van Zalinge, Steve Hall, Matthew Walker, Alexei Verkhratsky, Liam McDaid   +9 more
doaj   +1 more source