Results 181 to 190 of about 29,523 (243)

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy

, 2000
Gerhard J. Schütz, Gerald Kada, Vassili Ph. Pastushenko, Hansgeorg Schindler   +3 more
openalex   +2 more sources

Molecular Organization of Cholesterol in Polyunsaturated Membranes: Microdomain Formation [PDF]

, 2002
Michael R. Brzustowicz, Vadim Cherezov, Martin Caffrey, William Stillwell, Stephen R. Wassall   +4 more
openalex   +1 more source

Transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve neurotransmitter exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagrams of mammalian wild type (WT) (A) and Caspr‐KO (B) type‐I vestibular hair cells showing localization of the Caspr protein (orange), the Ca2+ conductance (green) and the low‐voltage‐activated K+ conductance (blue).
Paolo Spaiardi, Roberta Giunta, Giorgio Rispoli, Sergio Masetto, Stuart L. Johnson   +4 more
wiley   +1 more source

Interaction of syncollin with GP-2, the major membrane protein of pancreatic zymogen granules, and association with lipid microdomains [PDF]

, 2002
Ina Kalus, Alois Hodel, Annett Koch, Ralf Kleene, J. Michael Edwardson, Michael Schrader   +5 more
openalex   +1 more source

Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis

The Journal of Physiology, EarlyView.
Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley   +1 more source

Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus [PDF]

, 2002
Susan L. Kozak, Jean Michel Heard, David Kabat   +2 more
openalex   +1 more source

Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double‐blind, randomized controlled DHA‐WIN trial

International Journal of Cancer, Volume 157, Issue 7, Page 1405-1419, 1 October 2025.
What's New? Omega‐3 docosahexaenoic acid (DHA) has shown pleiotropic anti‐cancer effects both in vitro and in animal models. However, clinical evidence of DHA efficacy is limited. This randomized, double‐blind, placebo‐controlled trial tested the efficacy of supplementation with DHA 4.4 g/day during 18 weeks of breast cancer neoadjuvant chemotherapy ...
Jaqueline Munhoz, Marnie Newell, Gilbert Bigras, Susan Goruk, Anil Abraham Joy, Sunita Ghosh, Kerry S. Courneya, Vera Mazurak, Claire M. Douglas, Xiaofu Zhu, Bohdarianna Zorniak, John Mackey, Judith Meza Junco, Julie Price Hiller, Karen King, Sanraj K. Basi, Catherine J. Field   +16 more
wiley   +1 more source

GPI‐microdomains (membrane rafts) and signaling of the multi‐chain interleukin‐2 receptor in human lymphoma/leukemia T cell lines [PDF]

, 2002
János Matkó, Andrea Bodnár, György Vereb, László Bene, György Vámosi, Gergely Szentesi, János Szöllősi, Rezső Gáspár, Václav Hořejšı́, Thomas A. Waldmann, Sándor Damjanovich   +10 more
openalex   +1 more source

Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics

MedComm, Volume 6, Issue 9, September 2025.
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia, Quan Liu, Wenli Zhang, Jinwen Ge, Zhigang Mei   +4 more
wiley   +1 more source