Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Donnan Membrane Potential [PDF]
IN a recent communication in NATURE (July 17, 1943, p. 76) I applied the Boltzmann distribution law to the Donnan membrane equilibrium between two compartments, compartment (1) containing colloidal (or non-diffusible) ions plus diffusible ions, compartment (2) containing only diffusible ions. From the equations obtained, it follows that at the same pH.
openaire +2 more sources
Macroscopic tunneling of a membrane in an optomechanical double-well potential
The macroscopic tunneling of an optomechanical membrane is considered. A cavity mode which couples quadratically to the membranes position can create highly tunable adiabatic double-well potentials, which together with the high Q-factors of such ...
Buchmann, L. F. +3 more
core +1 more source
Investigating membrane breakdown of neuronal cells exposed to nonuniform electric fields by finite-element modeling and experiments [PDF]
High electric field strengths may induce high cell membrane potentials. At a certain breakdown level the membrane potential becomes constant due to the transition from an insulating state into a high conductivity and high permeability state.
Heida, Tjitske +3 more
core +3 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Membrane repair against H. pylori promotes cancer cell proliferation [PDF]
Membrane repair is a universal response against physical and biological insults and enables cell survival. Helicobacter pylori is one of the most common human pathogens and the first formally recognized bacterial carcinogen associated with gastric cancer.
Chiung-Nien Chen +5 more
core +1 more source
Effective zero-thickness model for a conductive membrane driven by an electric field
The behavior of a conductive membrane in a static (DC) electric field is investigated theoretically. An effective zero-thickness model is constructed based on a Robin-type boundary condition for the electric potential at the membrane, originally ...
B. Hille +9 more
core +1 more source
Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation [PDF]
We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane potential during the cortical
Barry, Melissa +4 more
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The neurons in the inferior olive express subthreshold oscillations in their membrane potential. This oscillatory activity is known to drive synchronous activity in the cerebellar cortex and plays a role in motor learning and motor timing.
Paolo Bazzigaluppi, Marcel T G De Jeu
doaj +1 more source

