Results 201 to 210 of about 14,870,238 (380)

The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres

, 1969
O Hauswirth, Denis Noble, Richard W. Tsien   +2 more
openalex   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.

Cell Metabolism, 2016
M. Sukumar, Jie Liu, Gautam U. Mehta, Shashank J. Patel, R. Roychoudhuri, Joseph G Crompton, C. Klebanoff, Yun Ji, Peng Li, Zhiya Yu, G. Whitehill, D. Clever, R. Eil, D. Palmer, S. Mitra, Mahadev Rao, K. Keyvanfar, D. Schrump, E. Wang, F. Marincola, L. Gattinoni, W. Leonard, P. Muranski, T. Finkel, N. Restifo   +24 more
semanticscholar   +1 more source

Membrane potential and ion content in the smooth muscle of the guinea‐pig's taenia coli at different external potassium concentrations

, 1966
R. Casteels, H Kuriyama
openalex   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Effects of sodium extrusion and local anaesthetics on muscle membrane resistance and potential

, 1966
E. J. Harris, Sidney Ochs
openalex   +2 more sources

The effects of temperature on the membrane potentials in isolated atria of the ground squirrel, Citellus tridecemlineatus [PDF]

, 1962
Jean M. Marshall, J.S. Willis
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Analysis of mitochondrial membrane potential, ROS, and calcium. [PDF]

Mol Cells
Park HK, Kang BH.
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source