Results 81 to 90 of about 14,693,728 (394)

Subthreshold dynamics of the neural membrane potential driven by stochastic synaptic input [PDF]

, 2002
In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of the background ...
A. Destexhe, B. Jagadeesh, C.M. Gray, C.M. Gray, D. Paré, D.A. McCormick, D.B. Jaffe, J. Defelipe, J.P. Aparicio, J.R. Huguenard, M. Andreasen, M. Castelo-Branco, M. Steriade, M. Steriade, M. Steriade, N. Brunel, P.E. Maldonado, R. Azouz, R.A. Chitwood, S. Friedman-Hill, U. Hillenbrand, Ulrich Hillenbrand, V. Bringuier, W. Gerstner, W. Rall   +24 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ, Brock, R, Cluitmans, JC, Dinkla, S, Fransen, J, Fuchs, B, Joosten, I, Schiller, J, Tomelleri, C, Verdurmen, WP, Wessels, K   +10 more
core   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Imaging mitochondrial membrane potentials

Biophysical Journal, 1993
process remain to be elucidated. The elusiveness of this goal can be attributed, at least in part, to the absence of structural information about the mitochondrion itself at several levels of complexity. It is obvious, for example, that obtaining atomic structures of the respiratory chain protein complexes by x-ray or electron crystallography would ...
openaire   +3 more sources

Ling’s Adsorption Theory as a Mechanism of Membrane Potential Generation Observed in Both Living and Nonliving Systems

Membranes, 2016
The potential between two electrolytic solutions separated by a membrane impermeable to ions was measured and the generation mechanism of potential measured was investigated.
Hirohisa Tamagawa, Makoto Funatani, Kota Ikeda   +2 more
doaj   +1 more source

Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles

Drug Delivery, 2022
Prostate cancer (PC) is emerging as one of the leading causes of mortality and morbidity worldwide. Curcumin (CUR) is a well-known phytochemical, and scorpion venom (SV) is a natural peptide with proven anticancer properties.
Mohammed W. Al-Rabia, Nabil A. Alhakamy, Waleed Y. Rizg, Adel F. Alghaith, Osama A. A. Ahmed, Usama A. Fahmy   +5 more
doaj   +1 more source

Tension moderation and fluctuation spectrum in simulated lipid membranes under an applied electric potential

, 2013
We investigate the effect of an applied electric potential on the mechanics of a coarse grained POPC bilayer under tension. The size and duration of our simulations allow for a detailed and accurate study of the fluctuations.
Khandelia, Himanshu, Lomholt, Michael Andersen, Loubet, Bastien   +2 more
core   +1 more source

Cellular binding of nanoparticles disrupts the membrane potential.

RSC Advances, 2015
All cells generate an electrical potential across their plasma membrane driven by a concentration gradient of charged ions. A typical resting membrane potential ranges from -40 to -70 mV, with a net negative charge on the cytosolic side of the membrane ...
Emilie Warren, C. Payne
semanticscholar   +1 more source