Results 81 to 90 of about 442,263 (324)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Membrane Potential

, 2014
Citation: 'membrane potential' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03825 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
A.A. Ramahi, R.L. Ruff
openaire   +2 more sources

Stochastic Dynamics of Electrical Membrane with Voltage-Dependent Ion Channel Fluctuations

, 2014
Brownian ratchet like stochastic theory for the electrochemical membrane system of Hodgkin-Huxley (HH) is developed. The system is characterized by a continuous variable $Q_m(t)$, representing mobile membrane charge density, and a discrete variable $K_t$
Qian, Hong, Qian, Min, Zhang, Xue-Juan
core   +1 more source

String-Membrane Duality in Seven Dimensions [PDF]

, 1995
The conjectured equivalence of the heterotic string to a $K_3$ compactified type IIA superstring is combined with the conjectured equivalence of the latter to a compactified 11-dimensional supermembrane to derive a string membrane duality in seven ...
Achúcarro, Bars, Bergshoeff, Bergshoeff, Bergshoeff, Callan, Callan, Dabholkar, Dabholkar, Dai, de Wit, Dine, Duff, Duff, Duff, Duff, Duff, Duff, Duff, Duff, Gates, Gauntlett, Gibbons, Gibbons, Güven, Harvey, Horowitz, Howe, Hull, Hull, Khuri, Khuri, Mezincescu, Nicolai, P.K. Townsend, Pope, Sen, Sen, Sierra, Strominger, Townsend, Townsend, Townsend, Townsend, Witten   +44 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Insight into the Mode of Action of Celangulin V on the Transmembrane Potential of Midgut Cells in Lepidopteran Larvae

Toxins, 2017
Celangulin V (CV) is the main insecticidal constituent of Celastrus angulatus. The V-ATPase H subunit of the midgut cells of lepidopteran larvae is the putative target protein of CV.
Yingying Wang, Jiwen Zhang, Mingxing Feng, Wenjun Wu, Zhaonong Hu   +4 more
doaj   +1 more source

Cortical Stimulation Induces Excitatory Postsynaptic Potentials of Inferior Colliculus Neurons in a Frequency-Specific Manner

Frontiers in Neural Circuits, 2020
Corticofugal modulation of auditory responses in subcortical nuclei has been extensively studied whereas corticofugal synaptic transmission must still be characterized.
Jiyao Qi, Zizhen Zhang, Na He, Xiuping Liu, Caseng Zhang, Jun Yan   +5 more
doaj   +1 more source

Multi-heme Cytochromes in Shewanella oneidensis MR-1:Structures, functions and opportunities [PDF]

, 2015
Multi-heme cytochromes are employed by a range of microorganisms to transport electrons over distances of up to tens of nanometers. Perhaps the most spectacular utilization of these proteins is in the reduction of extracellular solid substrates ...
Brown JP, Collins MJ, Coursolle D, Fonseca BM, Jochen Blumberger, Julea N. Butt, Kevin M. Rosso, Marian Breuer, Song Y, Teixeira M   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Menthol Modulates Pacemaker Potentials through TRPA1 Channels in Cultured Interstitial Cells of Cajal from Murine Small Intestine

Cellular Physiology and Biochemistry, 2016
Background/Aims: ICCs are the pacemaker cells responsible for slow waves in gastrointestinal (GI) smooth muscle, and generate periodic pacemaker potentials in current-clamp mode.
Hyun Jung Kim, Jinhong Wie, Insuk So, Myeong Ho Jung, Ki-Tae Ha, Byung Joo Kim   +5 more
doaj   +1 more source