Results 81 to 90 of about 228,598 (287)

ON THE DETERMINATION OF ELASTIC POTENTIAL OF SPHERICAL RUBBER MEMBRANES

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2012
If one wants to make strength analysis of rubber membrane having large deformation, he must know the elastic potential. Having used potentials of Mooney and K.F.
N K Galimov   +2 more
doaj  

Photolipid excitation triggers depolarizing optocapacitive currents and action potentials

open access: yesNature Communications
Optically-induced changes in membrane capacitance may regulate neuronal activity without requiring genetic modifications. Previously, they mainly relied on sudden temperature jumps due to light absorption by membrane-associated nanomaterials or water ...
Carlos A. Z. Bassetto   +6 more
doaj   +1 more source

MEMBRANE POTENTIALS AND CATAPHORETIC POTENTIALS OF PROTEINS [PDF]

open access: yesJournal of General Physiology, 1923
1. It has been shown in preceding publications that the membrane potentials of protein solutions or gels are determined by differences in the concentration of a common ion (e.g. hydrogen ion) inside a protein solution or protein gel and an outside aqueous solution free from protein, and that the membrane potentials can be calculated with a good degree ...
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Imaging mitochondrial membrane potentials

open access: yesBiophysical Journal, 1993
process remain to be elucidated. The elusiveness of this goal can be attributed, at least in part, to the absence of structural information about the mitochondrion itself at several levels of complexity. It is obvious, for example, that obtaining atomic structures of the respiratory chain protein complexes by x-ray or electron crystallography would ...
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Multitask learning of a biophysically-detailed neuron model.

open access: yesPLoS Computational Biology
The human brain operates at multiple levels, from molecules to circuits, and understanding these complex processes requires integrated research efforts.
Jonas Verhellen   +4 more
doaj   +1 more source

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