Results 31 to 40 of about 3,087,877 (362)
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
Lill, Roland +2 more
core +2 more sources
Functional implications of the exon 9 splice insert in GluK1 kainate receptors
eLifeKainate receptors are key modulators of synaptic transmission and plasticity in the central nervous system. Different kainate receptor isoforms with distinct spatiotemporal expressions have been identified in the brain.
Surbhi Dhingra +3 more
doaj +1 more source
Inhibition by Commercial Aminoglycosides of Human Connexin Hemichannels Expressed in Bacteria
Molecules, 2017 In addition to gap junctional channels that mediate cell-to-cell communication, connexins form hemichannels that are present at the plasma membrane. Since hemichannels are permeable to small hydrophilic compounds, including metabolites and signaling ...
Mariana C. Fiori +4 more
doaj +1 more source
Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]
, 2020 Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F. +12 more
core +2 more sources
Heliyon, 2023 In the renal collecting ducts, chloride reabsorption occurs through both transcellular and paracellular pathways. Recent literature highlights a functional interplay between both pathways.
Rawad Lashhab +4 more
doaj
Specific DNA-RNA Hybrid Recognition by TAL Effectors
Cell Reports, 2012 The transcription activator-like (TAL) effector targets specific host promoter through its central DNA-binding domain, which comprises multiple tandem repeats (TALE repeats).
Ping Yin +6 more
doaj +1 more source
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Nature Communications, 2020 Coronavirus main protease is essential for viral polyprotein processing and replication. Here Vuong et al. report efficient inhibition of SARS-CoV-2 replication by the dipeptide-based protease inhibitor GC376 and its parent GC373, which were originally ...
Wayne Vuong +13 more
doaj +1 more source
Structure and mechanism of membrane transporters
Scientific Reports, 2022 Membrane transporters are an important group of proteins in physiology and disease. Their functions make them common drug targets, but their location in the lipid bilayers poses a tremendous challenge to researchers.
Lan Guan
doaj +1 more source
Diffusing proteins on a fluctuating membrane: Analytical theory and simulations
, 2010 Using analytical calculations and computer simulations we consider both the lateral diffusion of a membrane protein and the fluctuation spectrum of the membrane in which the protein is embedded.
B. Alberts +5 more
core +1 more source
A new approach to immunoFET operation [PDF]
, 1990 A new method is presented for the detection of an immunological reaction taking place in a membrane, which covers the gate area of an ISFET. By stepwise changing the electrolyte concentration of the sample solution, a transient diffusion of ions through ...
Bergveld, P. +3 more
core +2 more sources