Results 161 to 170 of about 491,037 (213)

Phosphatidylserine regulates plasma membrane repair through tetraspanin-enriched macrodomains. [PDF]

J Cell Biol
Li YE, Norris DM, Xiao FN, Pandzic E, Whan RM, Fok S, Zhou M, Du G, Liu Y, Du X, Yang H.   +10 more
europepmc   +1 more source

Mitochondria-encoded peptide MOTS-c participates in plasma membrane repair by facilitating the translocation of TRIM72 to membrane. [PDF]

Theranostics
Jia H, Zhou LC, Chen YF, Zhang W, Qi W, Wang P, Huang X, Guo JW, Hou WF, Zhang RR, Zhou JJ, Zhang DW.   +11 more
europepmc   +1 more source

The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair

Heffner CM, Starling GP, Isaacs A, Carlton JG.   +3 more
europepmc   +1 more source

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Annexins in plasma membrane repair

Biological Chemistry, 2016
Abstract Disruption of the plasma membrane poses deadly threat to eukaryotic cells and survival requires a rapid membrane repair system. Recent evidence reveal various plasma membrane repair mechanisms, which are required for cells to cope with membrane lesions including membrane fusion and replacement strategies, remodeling of cortical ...
Jesper Nylandsted, Theresa Louise Boye
exaly   +3 more sources

Repairing the tears: dysferlin in muscle membrane repair

Trends in Molecular Medicine, 2003
Many muscular dystrophies arise from enhanced muscle degeneration, but one muscular dystrophy subtype has now been shown to arise from defective muscle membrane repair. Mutations in the gene encoding dysferlin cause muscular dystrophy, and recent work has demonstrated a role for this protein in resealing muscle membrane tears.
Katherine R, Doherty, Elizabeth M, McNally   +1 more
openaire   +2 more sources

The mechanism of cell membrane repair

Zygote, 1999
Disruption of plasma membranes is a widespread, common and normal event that occurs in many mechanically challenged tissues (McNeil & Steinhardt, 1997). After injury to the plasma membrane, rapid resealing of the membrane occurs with little loss of intracellular contents.Analysis of plasma membrane repair in the sea urchin egg and early embryos ...
T, Togo, J M, Alderton, R A, Steinhardt
openaire   +2 more sources

A kinetic model of membrane repair

Canadian Journal of Physiology and Pharmacology, 1970
Two microelectrodes are inserted into a Xenopus laevis egg. Rectangular current pulses are injected through one microelectrode and the voltage induced across the cell membrane is measured via the second electrode. The transmembrane resistance, as deduced from the injected current and the measured voltage, is taken as a measure of membrane integrity ...
J W, Prothero, R, Bulger, J, Chambers, N, Mack   +3 more
openaire   +2 more sources

Calcium and Membrane Repair

2010
As more and more studies utilize cell-penetrating peptides to deliver pharmacologically interesting substances, there is a growing need to understand their effect on the plasma membrane. If a cell-penetrating peptide together with its cargo is to be used as a drug, it is necessary to understand how the conjugate interacts with the plasma membrane to ...
Caroline, Palm-Apergi, Mattias, Hällbrink   +1 more
openaire   +2 more sources

Ceramide in Plasma Membrane Repair

2013
The perforation of the plasmalemma by pore-forming toxins causes an influx of Ca(2+) and an efflux of cytoplasmic proteins. In order to ensure cellular survival, lesions have to be identified, plugged and removed from the membrane. The Ca(2+)-driven fusion of lysosomes with the plasma membrane leads to hydrolysis of sphingomyelin by acid ...
Draeger A, Babiychuk EB
openaire   +4 more sources

Lysosomes and plasma membrane repair

2019
The ability of repairing damages on the plasma membrane is crucial for cell survival. When damaged, eukaryotic cells are able to recover plasma membrane integrity within a few seconds, thus avoiding cytoplasm leakage and cell death. The process is driven by the influx of extracellular calcium which triggers a multitude of intracellular effects that ...
Matthias, Corrotte, Thiago, Castro-Gomes
openaire   +2 more sources