Results 141 to 150 of about 26,768 (226)
Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation.
PLoS PathogensShigella flexneri is a human intracellular pathogen responsible for bacillary dysentery (bloody diarrhea). S. flexneri invades colonic epithelial cells and spreads from cell to cell, leading to massive epithelial cell fenestration, a critical determinant
Steven J Rolland +6 more
doaj +1 more source
Intraepithelial neutrophils in mammary, urinary and gall bladder infections
Veterinary Research, 2019 Neutrophil mobilization is a crucial response to protect the host against invading microorganisms. Neutrophil recruitment and removal have to be tightly regulated to prevent uncontrolled inflammation and excessive release of their toxic content causing ...
Dvir Mintz +4 more
doaj +1 more source
Transient domain formation in membrane-bound organelles undergoing maturation
, 2013 The membrane components of cellular organelles have been shown to segregate into domains as the result of biochemical maturation. We propose that the dynamical competition between maturation and lateral segregation of membrane components regulates domain
Dmitrieff, Serge, Sens, Pierre
core +3 more sources
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Evidence That Cytochrome \u3cem\u3eb\u3csub\u3e5\u3c/sub\u3e\u3c/em\u3e Acts as a Redox Donor in CYP17A1 Mediated Androgen Synthesis [PDF]
, 2016 Cytochrome P450 17A1 (CYP17A1) is an important drug target for castration resistant prostate cancer. It is a bi-functional enzyme, catalyzing production of glucocorticoid precursors by hydroxylation of pregnene-nucleus, and androgen biosynthesis by a ...
Denisov, Ilia G. +5 more
core +1 more source
Packaging Technology and Science, EarlyView.Utilisation of postconsumer recycled (PCR) plastic for food contact has safety concerns due to the potential presence of unapproved intentionally/non‐intentionally added substances, which can pose health and environmental risks if not removed during recycling.
Khairun Tumu +2 more
wiley +1 more source
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. [PDF]
, 2019 Cells have evolved diverse protein-based machinery to reshape, cut, or fuse their membrane-delimited compartments. Dynamin superfamily proteins are principal components of this machinery and use their ability to hydrolyze GTP and to polymerize into ...
Frost, Adam, Kalia, Raghav
core
Responsive Materials, EarlyView.We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin +3 more
wiley +1 more source
Safety Science and Technology, EarlyView.Thermal degradation mechanism and kinetic triplets of Nafion N115 were elucidated via TGA, kinetic compensation analysis, Sestak–Berggren reconstruction, quantum calculations, and GC–MS. A diffusion‐controlled model governs active pyrolysis, although persistent perfluorinated products were identified, highlighting environmental implications and ...
Fan Yang +6 more
wiley +1 more source
Undulated cylinders of charged diblock copolymers
, 2006 We study the cylinder to sphere morphological transition of diblock copolymers in aqueous solution with a hydrophobic block and a charged block. We find a metastable undulated cylinder configuration for a range of charge and salt concentrations which ...
Grason, Gregory M. +1 more
core +1 more source