Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies. [PDF]
J Clin Invest, 2023 Yu F, Qian Z.
europepmc +1 more source
Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications
Advanced Science, EarlyView.Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo +12 more
wiley +1 more source
Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7. [PDF]
Nat CommunButkovič R +12 more
europepmc +2 more sources
Flotillins in membrane trafficking and physiopathology. [PDF]
Biol CellBodin S +4 more
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells. [PDF]
Biol Open, 2023 Koike S +4 more
europepmc +1 more source
Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis
Advanced Science, EarlyView.ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai +15 more
wiley +1 more source
LEAP2 triggers retromer-mediated membrane trafficking of MOSPD2 to promote chemotaxis in teleost monocytes/macrophages. [PDF]
Zool ResZhu TF +6 more
europepmc +1 more source
Imaging of post-synaptic membrane trafficking in neuronal dendrites: progress, limitations, and new developments. [PDF]
Neurophotonics, 2023 Perrais D, Sposini S, Angibaud J.
europepmc +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source