Results 81 to 90 of about 1,517,613 (196)

SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism

Journal of Pharmacological Sciences, 2019
The serotonin transporter (SERT) is functionally regulated via membrane trafficking. Our previous studies have demonstrated that the SERT C-terminal deletion mutant (SERTΔCT) showed a robust decrease in its membrane trafficking and was retained in the ...
Masaya Asano, Serika Motoike, Chika Yokota, Naoto Usuki, Hikaru Yamamoto, Tomoaki Urabe, Kazusa Katarao, Izumi Hide, Shigeru Tanaka, Masashi Kawamoto, Masahiro Irifune, Norio Sakai   +11 more
doaj   +1 more source

Hypoxia-stimulated membrane trafficking requires T-plastin [PDF]

, 2017
Aim Traffic between the plasma membrane and the endomembrane compartments is an essential feature of eukaryotic cells. The secretory pathway sends cargoes from biosynthetic compartments to the plasma membrane.
Heidenreich, D., S. Naas, Katschinski, D. M., Lenz, C., J. Böttger, von Ahlen, M., Lutz, S., G. J. van Belle, Böttger, J., Möbius, W., van Belle, G., van Belle, G. J., K. Kröhnert, M. Wottawa, Zieseniss, A., Revelo, Natalia H., Katschinski, D., N. H. Revelo, W. Möbius, Rizzoli, S., S. O. Rizzoli, Urlaub, H., Rizzoli, S. O., Kröhnert, K., A. Zieseniss, Naas, S., M. von Ahlen, D. Heidenreich, H. Urlaub, D. M. Katschinski, Wottawa, M., Revelo, N., C. Lenz, S. Lutz   +33 more
core   +1 more source

Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells

Journal of Lipid Research, 2007
Niemann-Pick C1-like 1 protein (NPC1L1) is the putative intestinal sterol transporter and the molecular target of ezetimibe, a potent inhibitor of cholesterol absorption.
F. Jeffrey Field, Kim Watt, Satya N. Mathur   +2 more
doaj   +1 more source

Other title: Human trafficking

, 2016
Palm card.; "Mike DeWine, Ohio Attorney General."; "Created: 7/20/2016 ..."--Document properties screen.; "Protecting Ohio's Families."On verso: Recognizing the problem: Sex trafficking ; Labor trafficking ; Report suspicious ...

core  

Possible Roles of Membrane Trafficking Components for Lipid Droplet Dynamics in Higher Plants and Green Algae

Frontiers in Plant Science, 2019
Lipid droplets are ubiquitous dynamic organelles that contain neutral lipids surrounded by a phospholipid monolayer. They can store and supply lipids for energy metabolism and membrane synthesis.
Shuxian Huang, Liwen Jiang, Liwen Jiang, Xiaohong Zhuang   +3 more
doaj   +1 more source

Pathologies of Security Governance: Efforts Against Human Trafficking in Europe [PDF]

, 2007
The trafficking of women and girls for the purpose of sexual exploitation has reportedly been booming in Europe since the 1990s. Governments, international organizations, and private actors have addressed the causes and consequences of sex trafficking in
Friesendorf, Cornelius
core   +1 more source

Insights into the role of derailed endocytic trafficking pathway in cancer: From the perspective of cancer hallmarks

Pharmacological Research
The endocytic trafficking pathway is a highly organized cellular program responsible for the regulation of membrane components and uptake of extracellular substances. Molecules internalized into the cell through endocytosis will be sorted for degradation
Hongjie Guo, Chen Zhou, Mingming Zheng, Jie Zhang, Honghai Wu, Qiaojun He, Ling Ding, Bo Yang   +7 more
doaj   +1 more source

LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes.

PLoS ONE, 2014
Polarization of hepatocytes is manifested by bile canalicular network formation and activation of LKB1 and AMPK, which control cellular energy metabolism.
László Homolya, Dong Fu, Prabuddha Sengupta, Michal Jarnik, Jean-Pierre Gillet, Lynn Vitale-Cross, J Silvio Gutkind, Jennifer Lippincott-Schwartz, Irwin M Arias   +8 more
doaj   +1 more source

Rab35 GTPase and cancer: Linking membrane trafficking to tumorigenesis

, 2018
International audienceBrief synopsis: Rab35 is a small GTPase that was recently reported to possess oncogenic activating mutations in human tumors. Conversely, Rab35 depletion inverts apico-basal cell polarity and promotes cell migration.
Shaughnessy, Ronan, Ronan Shaughnessy, Echard, Arnaud, Arnaud Echard   +3 more
core   +1 more source

Intracellular trafficking of AQP2 in renal cells: from physiology to pathology

, 2012
The water channel Aquaporin 2 (AQP2) is responsible for the vasopressin (VP)-dependent water reabsorption occurring in the kidney during antidiuresis. X-linked nephrogenic diabetes insipidus (XNDI), a severe rare disease characterized by impaired urine-
PROCINO, Giuseppe, VALENTI, Giovanna, Barbieri C., Milano S. Carmosino M., SVELTO, Maria   +4 more
core