Results 111 to 120 of about 917,628 (315)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The organizing potential of sphingolipids in intracellular membrane transport

open access: yes, 2010
Eukaryotes are characterized by endomembranes that are connected by vesicular transport along secretory and endocytic pathways. The compositional differences between the various cellular membranes are maintained by sorting events, and it has long been ...
Raggers, R.J.   +7 more
core  

The sodium-dependent D-glucose transport protein of Helicobacter pylori

open access: yes, 2008
Helicobacter pylori is a gram-negative pathogenic microaerophile with a particular tropism for the mucosal surface of the gastric epithelium. Despite its obligatory microaerophilic character, it can metabolize D-glucose and/or D-galactose in both ...
Kim E. Bettaney   +21 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Removal of adsorbing estrogenic micropollutants by nanofiltration membranes:Part B-Model development

open access: yes, 2013
Removal of estrone (E1) and estradiol (E2) by nanofiltration membranes at neutral pH is carried out both by size exclusion and adsorption. Size exclusion is dependent on the solute to pore radius ratio and the hormone-membrane affinity. It has been shown
Schaefer, AndreaI.   +2 more
core   +1 more source

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

open access: yes, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Langsley, G   +20 more
core   +1 more source

R Version of the Kedem–Katchalsky–Peusner Equations for Liquid Interface Potentials in a Membrane System

open access: yesEntropy
Peusner’s network thermodynamics (PNT) is an important way of describing processes in nonequilibrium thermodynamics. PNT allows energy transport and conversion processes in membrane systems to be described.
Andrzej Ślęzak   +1 more
doaj   +1 more source

Preparation of Citric Acid Crosslinked Chitosan/Poly(Vinyl Alcohol) Blend Membranes for Creatinine Transport

open access: yesIndonesian Journal of Chemistry, 2016
Preparation of membrane using crosslinking reaction between chitosan and citric acid showed that functional group modification increased the number of active carrier groups which lead to better transport capacity of the membrane.
Retno Ariadi Lusiana   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]

open access: yes, 1999
The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess   +5 more
core   +1 more source

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