Results 51 to 60 of about 917,628 (315)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reduced-dimensional models for straight-channel proton exchange membrane fuel cells [PDF]

, 2010
A comprehensive description of proton exchange membrane fuel cell (PEMFC) performance includes the transport phenomena, phase change and electrochemical reaction inside the several components, which possess disparate characteristics and together form a ...
Sui, P.C., Shah, Akeel A., Shah, A.A., Sui, P. C., Kim, Gwang-Soo, Djilali, Ned   +5 more
core   +1 more source

Mechanism of Na+-dependent citrate transport from the structure of an asymmetrical CitS dimer

eLife, 2015
The common human pathogen Salmonella enterica takes up citrate as a nutrient via the sodium symporter SeCitS. Uniquely, our 2.5 Å x-ray structure of the SeCitS dimer shows three different conformations of the active protomer.
David Wöhlert, Maria J Grötzinger, Werner Kühlbrandt, Özkan Yildiz   +3 more
doaj   +1 more source

Analyzing and Modeling of Water Transport Phenomena in Open-Cathode Polymer Electrolyte Membrane Fuel Cell

Applied Sciences, 2021
Water management is one issue that must be surpassed to ensure high membrane proton conductivity and adequate reactant transport in the membrane-electrode assembly (MEA) simultaneously.
Wei-Wei Yuan, Kai Ou, Seunghun Jung, Young-Bae Kim   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

From “Black Box” to a Real Description of Overall Mass Transport through Membrane and Boundary Layers

Membranes, 2019
The “black box” model defines the enhancement, the polarization modulus, and the intrinsic enhancement, without knowing the transport mechanism in the membrane.
Endre Nagy, Márta Vitai
doaj   +1 more source

Transport of Ciliary Membrane Proteins

Frontiers in Cell and Developmental Biology, 2020
Cilia and flagella are highly conserved organelles in eukaryotic cells that drive cell movement and act as cell antennae that receive and transmit signals.
Huan Long, Kaiyao Huang
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Trapped lipopolysaccharide and LptD intermediates reveal lipopolysaccharide translocation steps across the Escherichia coli outer membrane

, 2015
C.D. is a recipient of the Wellcome Trust Investigator award (WT106121MA). W.W. is supported by Science and Technology Program of Guangzhou, China (201510010040).Lipopolysaccharide (LPS) is a main component of the outer membrane of Gram-negative bacteria,
Dong, H., Li, Xuejun, Wang, W., Gu, Y., Dong, Changjiang, Li, X., Dong, C., Gu, Yinghong, Dong, Haohao, Wang, Wenjian   +9 more
core   +1 more source

Effects of membrane alterations on bacterial retention [PDF]

, 2010
The study shows the respective roles of skin and support of an ultrafiltration membrane in the retention mechanisms of bacteria (Escherichia coli).
Causserand, Christel, Lebleu, Nathalie, Aimar, Pierre, Roques, Christine   +3 more
core   +1 more source