The lipid flippase MoNeo1 mediates vesicle trafficking and pathogenicity in Magnaporthe oryzae. [PDF]
Cai Y +12 more
europepmc +1 more source
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
Molecular and Physiological Regulation of Premature Leaf Senescence in Rice. [PDF]
Sun Y, Wang J, Yu Y, Wu L, Ruan B.
europepmc +1 more source
Clinical, histological, and serological predictors of renal function loss in lupus nephritis.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Lysosome trafficking across intracellular and intercellular networks in the brain. [PDF]
Murphy DT, Lo CH.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system. [PDF]
Ge X, Gu Z, Wang J.
europepmc +1 more source
The Rab5 effector Rabankyrin-5 mediates endosomal fusion and trafficking of human papillomavirus during early entry. [PDF]
Love M, Dang RC, Xie J, Zhang P.
europepmc +1 more source
Transporters, an important but poorly studied area of Toxoplasma gondii. [PDF]
Wang L +8 more
europepmc +1 more source

