Results 61 to 70 of about 1,050,062 (243)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The EXO70 inhibitor Endosidin2 alters plasma membrane protein composition in Arabidopsis roots

Frontiers in Plant Science, 2023
To sustain normal growth and allow rapid responses to environmental cues, plants alter the plasma membrane protein composition under different conditions presumably by regulation of delivery, stability, and internalization.
Xiaohui Li, Xiaohui Li, Peipei Zhu, Peipei Zhu, Yen-Ju Chen, Yen-Ju Chen, Lei Huang, Lei Huang, Diwen Wang, Diwen Wang, David T. Newton, Chuan-Chih Hsu, Guang Lin, Guang Lin, W. Andy Tao, W. Andy Tao, Christopher J. Staiger, Christopher J. Staiger, Christopher J. Staiger, Chunhua Zhang, Chunhua Zhang   +20 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Hydrogen-Deuterium Exchange Mass-Spectrometry of Secondary Active Transporters: From Structural Dynamics to Molecular Mechanisms

Frontiers in Pharmacology, 2020
Membrane transporters allow the selective transport of otherwise poorly permeable solutes across the cell membrane and thus, play a key role in maintaining cellular homeostasis in all kingdoms of life.
Moshe Giladi, Moshe Giladi, Daniel Khananshvili   +2 more
doaj   +1 more source

ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]

, 2014
In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The MAL proteolipid is necessary for the overall apical delivery of membrane proteins in the polarized epithelial Madin-Darby canine kidney and Fischer rat thyroid cell lines [PDF]

, 2000
The MAL proteolipid has been recently demonstrated as being necessary for correct apical sorting of the transmembrane influenza virus hemagglutinin (HA) in Madin-Darby canine kidney (MDCK) cells.
Alonso, Miguel A., Martín-Belmonte, Fernando, Millán, Jaime, Puertollano, Rosa   +3 more
core   +2 more sources

Computational estimates of membrane flow and tension gradient in motile cells. [PDF]

PLoS ONE, 2014
All parts of motile cells, including the plasma membrane, have to translocate in the direction of locomotion. Both directed intracellular membrane transport coupled with polarized endo- and exocytosis and fluid flow in the plane of the plasma membrane ...
Ben Fogelson, Alex Mogilner
doaj   +1 more source

Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane

Nature Communications
The molecular mechanisms underlying the transport of influenza A virus (IAV) membrane proteins to the cell surface remain largely unclear. In this study, siRNA screening identifies Rab27a as a critical host factor regulating this transport process.
Tong Chen, Aotian Ouyang, Jiahui Zou, Yi Feng, Changsong Wu, Meijun Jiang, Shaoyu Tu, Ling Ding, Yanqing Cheng, Wenshuo Hu, Wei Sheng, Yanglin Li, Meilin Jin, Huanchun Chen, Hongbo Zhou   +14 more
doaj   +1 more source

Activity assay of membrane transport proteins [PDF]

Acta Biochimica et Biophysica Sinica, 2008
Membrane transport proteins are integral membrane proteins and considered as potential drug targets. Activity assay of transport proteins is essential for developing drugs to target these proteins. Major issues related to activity assessment of transport proteins include availability of transporters, transport activity of transporters, and interactions
openaire   +2 more sources