Results 91 to 100 of about 360,735 (316)

Diphtheria toxin T-domain as a tool for inducing lipid vesicle fusion

open access: yesCommunications Chemistry
Membrane fusion is fundamental for many biological processes, including subcellular compartmentalization, cell growth, and exo- and endocytosis. It also plays a key role in the fabrication of artificial membrane structures, particularly vesicles. However,
Piotr Jasko   +5 more
doaj   +1 more source

Biomimetic superstructures from amphiphilic ABA-triblock copolymers [PDF]

open access: yes, 2005
The spontaneous formation of nanostructured materials by molecular self-assembly of block copolymers is an active area of research, driven both by its inherent beauty and by a wealth of potential technological applications. The so-called “supramolecular”
Grumelard, Julie
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Ciliary and Flagellar Membrane Vesicle (Ectosome) Purification

open access: yesBio-Protocol, 2014
Eukaryotic cilia/flagella are ideal organelles for the analysis of membrane trafficking, membrane assembly, and the functions of a variety of signal transduction molecules.
William Dentler
doaj   +1 more source

Double membrane formation in heterogeneous vesicles

open access: yesSoft Matter, 2020
Coarse-grained models show double membrane formation from single-membrane, heterogeneous liposomes in the presence of small, hydrophobic molecules.
Dima Bolmatov   +4 more
openaire   +3 more sources

Extracellular membrane vesicles from keratinocytes

open access: yes, 2017
This project was the first to simultaneously study the three different types of extracellular membrane vesicles (EVs) released by skin cells in order to reveal the differences in their bioactive molecular cargo.
Than, Thi Trang Uyen
core   +1 more source

An efficient method for introducing defined lipids into the plasma membrane of mammalian cells [PDF]

open access: yes, 1983
An efficient method has been devised to introduce lipid molecules into the plasma membrane of mammalian cells. This method has been applied to fuse lipid vesicles with the apical plasma membrane of Madin-Darby canine kidney cells. The cells were infected
G van Meer   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Uptake of Helicobacter pylori Vesicles Is Facilitated by Clathrin-Dependent and Clathrin-Independent Endocytic Pathways

open access: yesmBio, 2014
Bacteria shed a diverse set of outer membrane vesicles that function as transport vehicles to deliver effector molecules and virulence factors to host cells.
Annelie Olofsson   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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