Results 131 to 140 of about 2,949,634 (335)

Quantitative Proteomic Analysis of Biogenesis-Based Classification for Extracellular Vesicles

Proteomes, 2020
Extracellular vesicles (EVs) are traditionally divided into two major groups: (i) large vesicles originating from plasma membrane and called microvesicles, and (ii) small vesicles originating from the endoplasmic membrane and called exosomes. However, it
Linwen Zhang, Jeremie Parot, Vincent A. Hackley, Illarion V. Turko   +3 more
doaj   +1 more source

Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication [PDF]

, 2012
All positive strand RNA viruses are known to replicate their genomes in close association with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family Flaviviridae, infected cells contain accumulations of vesicles forming ...
Antony, Claude, Bartenschlager, Ralf, Chiramel, Abhilash, Chlanda, Petr, Habermann, Anja, Haselman, Uta, Hoppe, Simone, Kallis, Stephanie, Krijnse-Locker, Jacomine, Lee, Ji-Young, Merz, Andreas, Romero-Brey, Inés, Santarella-Mellwig, Rachel, Walther, Paul   +13 more
core   +3 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Gi Protein Modulation of the Potassium Channel TASK-2 Mediates Vesicle Osmotic Swelling to Facilitate the Fusion of Aquaporin-2 Water Channel Containing Vesicles

Cells, 2018
Vesicle fusion is a fundamental cell biological process similar from yeasts to humans. For secretory vesicles, swelling is considered a step required for the expulsion of intravesicular content.
Mariangela Centrone, Maria Penelope De Santo, Isabella Nicotera, Cristina Labate, Marianna Ranieri, Annarita Di Mise, Maria Grazia Mola, Maria Mastrodonato, Rosangela Elliani, Riccardo Barberi, Vincenzo Formoso, Grazia Tamma, Giovanna Valenti   +12 more
doaj   +1 more source

Tubulation pattern of membrane vesicles coated with bio filaments

, 2018
Narrow membrane tubes are commonly pulled out from the surface of phospholipid vesicles using forces applied either through laser or magnetic tweezers or through the action of processive motor proteins.
Kumar, Gaurav, Ramakrishnan, N., Sain, Anirban   +2 more
core   +1 more source

Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles

International Journal of Molecular Sciences, 2016
Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane vesicles, with distinct biogenesis routes, biophysical properties and different functions both in physiological conditions and in disease. The release of EVs is a widespread
N. Iraci, T. Leonardi, F. Gessler, B. Vega, S. Pluchino   +4 more
semanticscholar   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Bacterial outer membrane vesicles and vaccine applications [PDF]

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo, Acosta, Armando, Campa, Concepcion, Cardoso, Daniel, Fernandez, Sonsire, Ferro, Valerie, Garcia, Luis, Perez, Jose Luis, Rosenqvist, Einar, Sarmiento, Maria Elena, Zayas, Caridad   +10 more
core   +2 more sources

Nanoplasmonic sensors for extracellular vesicles and bacterial membrane vesicles

Nano Convergence
AbstractExtracellular vesicles (EVs) are promising tools for the early diagnosis of diseases, and bacterial membrane vesicles (MVs) are especially important in health and environment monitoring. However, detecting EVs or bacterial MVs presents significant challenges for the clinical translation of EV-based diagnostics.
Aparna Neettiyath, Kyungwha Chung, Wenpeng Liu, Luke P. Lee   +3 more
openaire   +3 more sources

Bacterial membrane vesicles: Biogenesis, immune regulation and pathogenesis

Cellular Microbiology, 2016
Outer membrane vesicles were first described approximately 50 years ago and for many years were considered to be an artifact of bacterial growth. Since that initial discovery, it has become evident that outer membrane vesicles are produced by almost all ...
R. Pathirana, M. Kaparakis-Liaskos
semanticscholar   +1 more source