Results 31 to 40 of about 145,718 (267)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Validating Membrane Ageing Protocols: A Real‐World Perspective on Vanadium Redox Flow Battery Degradation

open access: yesChemElectroChem
Membranes are essential for an efficient and stable long‐term operation of the vanadium redox flow battery (VRFB). Membrane degradation is one of the main limiting factors for VRFB lifetime because of the resulting increase in electrolyte crossover and ...
Felix Lulay   +4 more
doaj   +1 more source

How Does Carbon Dioxide Permeate Cell Membranes?A discussion of concepts, results and methods.

open access: yesFrontiers in Physiology, 2014
We review briefly how the thinking about the permeation of gases, especially CO2, across cell and artificial lipid membranes has evolved during the last hundred years.
Volker eEndeward   +3 more
doaj   +1 more source

Identifying and Manipulating Giant Vesicles: Review of Recent Approaches

open access: yesMicromachines, 2022
Giant vesicles (GVs) are closed bilayer membranes that primarily comprise amphiphiles with diameters of more than 1 μm. Compared with regular vesicles (several tens of nanometers in size), GVs are of greater scientific interest as model cell membranes ...
Taro Toyota, Yiting Zhang
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Rational ion transport management mediated through membrane structures

open access: yesExploration, 2021
Unique membrane structures endow membranes with controlled ion transport properties in both biological and artificial systems, and they have shown broad application prospects from industrial production to biological interfaces.
Yupeng Chen   +3 more
doaj   +1 more source

A Practical Guide to Preparation and Applications of Giant Unilamellar Vesicles Formed via Centrifugation of Water-in-Oil Emulsion Droplets

open access: yesMembranes, 2023
Giant vesicles (GVs), which are closed lipid bilayer membranes with a diameter of more than 1 μm, have attracted attention not only as model cell membranes but also for the construction of artificial cells.
Yiting Zhang, Haruto Obuchi, Taro Toyota
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Reductionism redux

open access: yeseLife, 2016
Experiments on artificial membranes are revealing many details about the workings of a family of potassium ion channels called GIRK channels.
Christopher Miller
doaj   +1 more source

Photosensitive ion channels in layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers

open access: yesNature Communications, 2023
Artificial ion channels are in demand for ionotronic devices. Here, the authors use layered MXene membranes modified with plasmonic gold nanostars and cellulose nanofibers to convert a thermal gradient into an ion current for photosensitive ion ...
Jeonghee Yeom   +12 more
doaj   +1 more source

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