Results 181 to 190 of about 25,462 (288)

Advances in Erectile Dysfunction Management: What Does Work

Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen, Daye Park, Jasper Bash, Juan Andino   +3 more
wiley   +1 more source

Comparison of the efficacy of low, moderate and standard doses of rituximab in the treatment of membranous nephropathy. [PDF]

Front Med (Lausanne)
Guo M, Wan W, Li J, Wu S, Ruan Z, Wang R, Zhang Z, Geng X, Hu X, Ren H.   +9 more
europepmc   +1 more source

Randomised, phase 1 evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of iptacopan in healthy volunteers

British Journal of Pharmacology, Volume 183, Issue 11, Page 2874-2889, June 2026.
Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva, Guido Junge, Kenneth Kulmatycki, Robert Schmouder, Anna Schubart, Marie‐Anne Valentin   +5 more
wiley   +1 more source

Obinutuzumab Versus Rituximab for the Treatment of Primary Membranous Nephropathy: A Systematic Review and Meta-Analysis. [PDF]

Life (Basel)
Lurie A, Daneii P, Khan S, Khan Z, Mansuri H, Bizanti A.   +5 more
europepmc   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Autophagy in the Pathogenesis of Membranous Nephropathy. [PDF]

Kidney Med
Ponticelli C, Reggiani F, Moroni G.
europepmc   +1 more source

Durvalumab-associated membranous nephropathy: a case report and brief literature review. [PDF]

CEN Case Rep
Mizoguchi R, Tashiro T, Sakakima M.
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

COL12A1 rs970547 Polymorphism Predisposes Anterior Cruciate Ligament Injury by Inducing ER Stress and Impairing Fibroblast Function

Advanced Biology, Volume 10, Issue 5, May 2026.
The COL12A1 rs970547(A/A) polymorphism is over‐represented in Chinese male anterior cruciate ligament (ACL) injury patients. This variant destabilizes COL12A1 protein without altering transcript levels, driving compensatory upregulation of other collagen genes and inducing endoplasmic reticulum stress in ACL‐derived fibroblasts.
Wenchuan Zhao, Hong Chen, Junwei Wang, Yixin Li, Rui Chen, Jingyi Zhou   +5 more
wiley   +1 more source

Povetacicept for IgA Nephropathy and Primary Membranous Nephropathy. [PDF]

Kidney Int Rep
Madan A, Yalavarthy R, Kim DK, Moon JY, Park I, Mandayam S, Cortazar F, Kim SG, Enstrom A, Thomas H, Li J, Peng SL, Chen YC, Sanders J, Egbuna O, Tumlin J, AIS-D03 RUBY-3 Study Group.   +16 more
europepmc   +1 more source