Results 181 to 190 of about 15,079 (253)
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Concurrence of renal amyloidosis and membranous nephropathy: a case series and literature review. [PDF]
Li L, Wu Y, Hu Z.
europepmc +1 more source
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu +7 more
wiley +1 more source
Anti-PLA2R antibodies: implications for therapeutic planning and the prediction of remission in membranous nephropathy. [PDF]
Mastroianni-Kirsztajn G +2 more
europepmc +1 more source
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi +7 more
wiley +1 more source
The PLA2R Paradox: Seropositive Membranous Nephropathy With Negative Staining. [PDF]
Tang X +6 more
europepmc +1 more source
This work reviews how the metabolic by‐product methylglyoxal may contribute to the development of diabetic peripheral neuropathy (DPN), a common complication of diabetes characterized by nerve damage and chronic pain in the extremities. In diabetes, methylglyoxal levels rise due to increased glucose metabolism and reduced detoxification capacity. While
Gentry Totta‐Griese, Douglas E. Wright
wiley +1 more source
Spontaneous Remission of Late Relapsing Membranous Nephropathy After Previous Immunosuppressant-Induced Remission: Case Report. [PDF]
Cao Y.
europepmc +1 more source
Persistent Haematuria Is Associated With Reduced Kidney Survival in Primary Podocytopathies
ABSTRACT Aim Haematuria is frequently present in podocytopathies, but its significance and prognostic value are not well described. This study aimed to determine the prevalence and association between persistent haematuria and kidney survival in patients with membranous nephropathy (MN), minimal change disease (MCD) and focal segmental ...
Gabriel Ștefan +3 more
wiley +1 more source

