Results 191 to 200 of about 15,079 (253)

Spontaneously Resolving Pancreatic IgG4-Related Disease Representing With Systemic Involvement and Membranous Nephropathy. [PDF]

Kidney Med
Raza IGA, Smith SW, Chanouzas D.
europepmc   +1 more source

Amino acid homeostasis in the kidney: Physiological roles and pathological dysregulation

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Amino acids are fundamental to life as protein building blocks and key regulators of metabolism and signaling. The kidney plays a critical, yet underappreciated, role in amino acid homeostasis through three interconnected pillars: selective glomerular filtration, efficient tubular reabsorption, and metabolic processing, which includes de novo ...
Shuo Liu, Caifeng Shi, Yang Zhou, Chunsun Dai   +3 more
wiley   +1 more source

Obinutuzumab in the treatment of idiopathic refractory membranous nephropathy: an observational case series. [PDF]

Front Med (Lausanne)
Zhao X, Chang X, Wang Y, Chen D, Yu M, Zhao J, Zhu H, Mao Y, Juan C.   +8 more
europepmc   +1 more source

Ubiquitination‐Related Diagnostic Biomarkers for Diabetic Nephropathy: Insights From Multiomic Analysis, Drug Docking, and Experimental Validation

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
The Graphical Abstract demonstrates our research approach. Use GEO database to screen differentially expressed genes (DEGs), and weighted gene co expression network analysis (WGCNA) to identify ubiquitination related gene modules. The LASSO logistic regression and support vector machine recursive feature elimination (SVM‐RFE) algorithm is used to ...
Ting Dong, Miao Hu, Haibo Yu, Ling Zhou, Qing Qiao   +4 more
wiley   +1 more source

Severe anaphylactic shock reaction upon rituximab rechallenge in membranous nephropathy: a case report and literature review. [PDF]

Front Pharmacol
Huang W, Xu Y, Jin X, Zhang Q, Xiang T, Lei W.   +5 more
europepmc   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Membranous nephropathy secondary to very early-onset inflammatory bowel disease in a 3-year-old boy: case report. [PDF]

CEN Case Rep
Aoyama S, Yamamura T, Horinouchi T, Kimura Y, Inoki Y, Sakakibara N, Nagano C, Ishimori S, Kameoka Y, Kajihara K, Miyauchi H, Ku Y, Miyazaki H, Okamoto N, Yoshikawa N, Nozu K.   +15 more
europepmc   +1 more source

Targeting YAP1‐Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
YAP1 mediates tubular cell senescence and drives maladaptive repair following AKI, promoting the AKI to CKD transition. Single‐cell RNA‐seq reveals sustained YAP1 overexpression, fibroblast activation, and pro‐fibrotic tubular cell shift. Senolytic agents or verteporfin (YAP1/TEAD1 inhibitor) suppress YAP1 activity, reduce renal senescence, alleviate ...
Zhibo Zhao, Huiping An, Yonghou Sang, Si Chen, Jinxiu Zhou, Tingting Zhang, Junhu Li, Xiaoshuang Zhou   +7 more
wiley   +1 more source

Autophagy in the Pathogenesis of Membranous Nephropathy. [PDF]

Kidney Med
Ponticelli C, Reggiani F, Moroni G.
europepmc   +1 more source

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source