Results 171 to 180 of about 15,079 (253)

Case Report: A case of rituximab for membranous nephropathy secondary to primary Sjogren's syndrome and literature review. [PDF]

Front Immunol
Fu X, Gao F, Zang L, Mao N.
europepmc   +1 more source

Down‐Regulation of TFEB With Defective Autophagy in the Susceptibility of Aging Kidneys to Septic Acute Kidney Injury

Aging Cell, Volume 25, Issue 8, August 2026.
Aging is associated with impaired TFEB‐dependent autophagy in renal proximal tubular epithelial cells, leading to increased susceptibility to LPS‐induced injury and inflammation. Restoration of autophagy through TFEB activation or Tat–Beclin 1 treatment partially rescues autophagic function and confers protection against elderly sepsis‐associated acute
Yu Xiang, Ying Fu, Zhiwen Liu, Yu Han, Wenwen Wu, Juan Cai, Dongshan Zhang, Zheng Dong   +7 more
wiley   +1 more source

Rituximab for the treatment of membranous nephropathy in a patient with ankylosing spondylitis: a case report. [PDF]

Front Med (Lausanne)
Zhong R, Su L, Li H, Zhu H, Xiao Z.
europepmc   +1 more source

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice

British Journal of Pharmacology, Volume 183, Issue 16, Page 4919-4938, August 2026.
The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang, Zhuo Chen, Youzhi Wu, Thanh‐Truc Nguyen, Jingjing Wang, David M. Klyne, Zhi Ping Xu, Chen Chen, Alan Rowan, Felicity Y. Han   +9 more
wiley   +1 more source

PLA2R-Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report. [PDF]

Clin Case Rep
Abreham B, Hamza L, Kebede A, Bekele DR, Amdemariam Z.   +4 more
europepmc   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, Volume 183, Issue 16, Page 5102-5119, August 2026.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

Comparison of the efficacy of obinutuzumab versus rituximab combined with tacrolimus in the treatment of refractory membranous nephropathy. [PDF]

BMC Nephrol
Zhang Y, Guo M, Bian Q, Li S, Sun J, Qin Z, Xu J, Dong R.   +7 more
europepmc   +1 more source

MAFF Suppresses Necroptosis in Pancreatic Cancer via the GATA4‐MLKL Axis

Cancer Science, Volume 117, Issue 8, Page 2181-2193, August 2026.
MAFF promotes pancreatic cancer progression by acting as a transcriptional repressor of the GATA4‐MLKL axis, thereby inhibiting necroptotic cell death. This study identifies the MAFF‐GATA4‐MLKL pathway as a novel therapeutic target and a significant prognostic biomarker for pancreatic adenocarcinoma.
Xinwei Zhou, Zheng Zhao, Ning Sun, Daoyong Zhang   +3 more
wiley   +1 more source

A membranous nephropathy variant mimicking minimal change disease. [PDF]

J Pathol Clin Res
Pan C, Xiang S, Jiang M, Li Y, Huang B, Ye T, Du Y, Tang X, Yuan Y.   +8 more
europepmc   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, Volume 59, Issue 8, August 2026.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source