Results 81 to 90 of about 105,016 (295)

Sarcoidosis Presenting with Membranous Nephropathy in a Patient with Hypertensive Nephropathy: Case Report

open access: yesTurkish Journal of Nephrology, 2019
Sarcoidosis is a systemic granulomatous disease that primarily involves the lung but may also have renal involvement. We present a hypertensive nephrosclerosis case found to have sarcoidosis after membranous nephropathy was diagnosed.
Mehmet Nuri TURAN   +8 more
doaj  

Transplant Outcomes in Patients with Idiopathic Membranous Nephropathy

open access: yesInternational Journal of Nephrology, 2013
Background. The natural history of idiopathic membranous nephropathy and recurrent disease in transplants is variable. We performed a retrospective cohort study of renal transplant recipients with a primary diagnosis of idiopathic membranous nephropathy.
Claire Kennedy   +4 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Membranous Nephropathy: From Research Bench to Personalized Care

open access: yes, 2021
Membranous nephropathy is a glomerulopathy that causes nephrotic syndrome and, in at least a third of cases, lasting end-stage kidney disease (ESKD). It is also a rare case of revolutionary changes in our understanding of the disease, that translates ...
Barbara Moszczuk   +3 more
core   +1 more source

Targeting Renal IGFBP7 With Tetrahedral Framework Nucleic Acid‐Delivered siRNA Alleviates Acute Kidney Injury

open access: yesiNew Medicine, EarlyView.
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Objective Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted ...
Shao‐qi Wu   +11 more
wiley   +1 more source

A Phenome-Wide Association and Mendelian Randomization Study of Genetically Predicted Membranous Nephropathy with Multiple Diseases

open access: yesKidney & Blood Pressure Research
Introduction: Membranous nephropathy constitutes a significant proportion of cases leading to end-stage renal disease. In such instances, the accurate distinction between primary and secondary forms is crucial for proper treatment ...
Alida Wenghaerbai   +4 more
doaj   +1 more source

Membranous Nephropathy Associated with Atheroembolism

open access: yes, 2017
Membranous nephropathy (MN) is one of the most common biopsy diagnoses in adults, and it has been associated with chronic infections, autoimmune diseases, malignancies, and drugs.
Tamiko Takemura   +2 more
core   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

open access: yesiNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang   +5 more
wiley   +1 more source

PLA2-R positive primary membranous nephropathy: a case report [PDF]

open access: yes
Membranous nephropathy (MN) is a significant cause of nephrotic syndrome in adults, often linked to the presence of circulating antibodies against phospholipase A2 receptor (PLA2R).
Dzul Caballero, José Emmanuel   +4 more
core   +1 more source

Neural epidermal growth factor-like 1 expression predicts end-stage renal disease in phospholipase A2 receptor–negative membranous nephropathy: A retrospective cohort stratified by systemic lupus erythematosus

open access: yesJournal of International Medical Research
Background Neural epidermal growth factor-like 1 protein has emerged as a significant antigen in membranous nephropathy, an important cause of nephrotic syndrome in adults.
Qingqing Rao   +6 more
doaj   +1 more source

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