Results 61 to 70 of about 25,462 (288)
Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]
, 1993 Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D +9 more
core +1 more source
Advanced Science, EarlyView.NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song +12 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2019 Objective To investigate the composition of chronic glomerular disease spectrum as well as the epidemiological characteristics of membranous nephropathy in Guangdong Provincial People’s Hospital in recent 18 years.
XIE Zhi-yong +10 more
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Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]
, 2018 Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo +14 more
core +1 more source
Advanced Science, EarlyView.Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
Transplant Outcomes in Patients with Idiopathic Membranous Nephropathy
International Journal of Nephrology, 2013 Background. The natural history of idiopathic membranous nephropathy and recurrent disease in transplants is variable. We performed a retrospective cohort study of renal transplant recipients with a primary diagnosis of idiopathic membranous nephropathy.
Claire Kennedy +4 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du +15 more
wiley +1 more source
Glomerulonefriit – märkamatult progresseeruv neerukahjustus [PDF]
, 2009 Glomerulonefriidid on põhiliselt immuungeneesiga neeru glomerulaarsed haigused, mille puhul esineb sageli ka põletikuline kahjustus. Glomerulonefriitide diagnostikas on oluline uriini analüüs, kus võib leida erinevas astmes proteinuuriat, hematuuriat ...
Luman, Merike
core +2 more sources
Advanced Science, EarlyView.PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang +17 more
wiley +1 more source
Turkish Journal of Nephrology, 2019 Sarcoidosis is a systemic granulomatous disease that primarily involves the lung but may also have renal involvement. We present a hypertensive nephrosclerosis case found to have sarcoidosis after membranous nephropathy was diagnosed.
Mehmet Nuri TURAN +8 more
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