Results 51 to 60 of about 368,964 (263)
El funcionamiento de los memoriales como lugares que recogen una memoria colectiva puede ser, como mínimo, problematizado. A lo largo del texto se reflexiona sobre la compleja relación que se establece entre la memoria y la historia no sólo en estas ...
Yayo Aznar
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
This article will aim to examine in depth Memorial by Rafael Cadenas, dedicated to his wife Milena and published in 1977, an important year that marks the continuation of his poetic production after eleven years of apparent silence.
Simone Marino Cicinelli
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This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Le tourisme obscur écologique d’une pandémie. Ce que pourrait être la mémoire de la COVID-19
If the COVID-19 pandemic were to remain in collective memory as a catastrophe shaking all of society and the whole world, it is possible that a kind of dark tourism will be developed around the pandemic.
Nathanael Wadbled
doaj
El espacio constituye un dispositivo fundamental en la articulación, reproducción y transformación de la memoria. Efectivamente resulta muy difícil evocar algún suceso sin que se piense en el lugar donde ha acaecido.
Angelique Trachana +1 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Le tourisme réflexif, un nouveau fondement d’un tourisme durable
El desarrollo del turismo sostenible se enfrenta con la dificultad de utilizar un discurso contradictorio, y más en un contexto en el que se dan grandes concentraciones turísticas y en el que los flujos turísticos se intensifican de día en día.
Rémy Knafou
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source

